Home Contact Sitemap

eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease sick sinus syndrome
Comorbidity C0037052|sick sinus syndrome
Sentences 19
PubMedID- 22707940 This condition, also known as sick sinus syndrome, occurs commonly within the aging adult population, but is particularly prevalent in patients with heart disease, on anti-arrhythmic therapy, with high vagal tone, or after surgical correction of congenital heart defects.
PubMedID- 25761764 Additionally, scn5a loss of function mutations are known to cause sick sinus syndrome66 where reduction in the flow of sodium ions alters the ability of the sa node to develop and spread electrical signals.
PubMedID- 21319337 The sick sinus syndrome occurs in 1 of every 600 cardiac patients older than 65 years and accounts for approximately half of implantations of pacemakers in the united states.1 a better understanding of the mechanisms of san automaticity and sick sinus syndrome is therefore clinically important.
PubMedID- 24223646 Twenty patients with sick sinus syndrome (sss) who had undergone the implantation of a dual-chamber pacemaker were enrolled in this study and the pacemakers were programmed to aai, ddd and vvi modes, sequentially.
PubMedID- 25510744 Catheter ablation for typical afl has been well established and ensures a high success rate and adequate safety.1 however, sick sinus syndrome (sss) is occasionally uncovered when long-term, persistent afl is terminated by ablation.2,3 permanent pacemaker implantation is necessary in these cases.
PubMedID- 25755643 Cardiac diseases, and specifically sick sinus syndrome, are associated with reduction in cell-cell junctional proteins (dobrzynski et al., 2007).
PubMedID- 24400285 Long qt syndrome (lqts), short qt syndrome (sqts), sick sinus syndrome (sss), cardiac conduction defect (ccd), brs, catecholaminergic polymorphic ventricular tachycardia (cpvt), early repolarization syndrome (ers), and familial atrial fibrillation (af) are the presently known cardiac channelopathies, which could occur due to a single or multiple defect in the genes linked to cardiac rhythm generation and propagation.
PubMedID- 24782956 [4] reported only one patient with svc obstruction and sick sinus syndrome postoperatively in a series of 40 patients who underwent the warden procedure.
PubMedID- 22737129 Severe forms of sick sinus syndrome have also been found in patients with double inheritance of scn5a loss-of-function mutations (benson et al., 2003).
PubMedID- 22966470 An 81-year-old man with a history of hypertension, diabetes, atrial flutter, and sick sinus syndrome presented to the hospital in july complaining of a 3-day history of fever, chills, rigors, myalgia, worsening hand tremors, lower extremity weakness, and difficulty in walking.
PubMedID- 24071461 Patients with sick sinus syndrome or cardiac conduction block in the atrium or of the atrioventricular junction (sinoatrial block or av block of 2° or more).
PubMedID- 23236009 The pacemaker had been placed to treat the patient's sick sinus syndrome, first diagnosed in 1994. his cardiovascular risk factors were arterial hypertension and non-insulin-dependent diabetes mellitus.
PubMedID- 24570728 Our patient additionally had sick sinus syndrome resulting in profound sinus bradycardia requiring permanent pacing, which cannot be provided by s-icds.
PubMedID- 24286219 Two patients required pacemaker implantation (4.7%) due to sick sinus syndrome and chronotropic incompetence in 6 months follow-up.
PubMedID- 24482563 An 81 year old female with sick sinus syndrome was admitted with near syncopal events in september 2010. she had underwent implantation of a 5mm medtronic 4057 unipolar active fixation atrial lead, mated to a 5/6mm connector port configuration medtronic spectrax sx 5985 single chamber pacemaker in 1990. pulse generator eri reached in 2006, and a medtronic sigma ssr306 (which also had the 5/6mm connector port configuration) was implanted, with preservation of the previous 5mm lead.
PubMedID- 24759974 Hereditary) sick sinus syndrome has been linked in various families to loss-of-function mutations in nav1.5 [21].
PubMedID- 25915951 Dysrhythmias, atrioventricular conduction delay and sick sinus syndrome were reported in sudden death in acromegalic heart disease [6].
PubMedID- 20606789 sick sinus syndrome is a dysfunction of the sinus node or sa conduction in which no adequate escape mechanism is present and the patient becomes symptomatic because of the bradycardia.
PubMedID- 20369066 An 82-year-old lady with 10-year history of diabetes mellitus, hypertension, and sick sinus syndrome presented in february 2008 with anaemia and thrombocytopenia.

Page: 1