Disease | severe combined immunodeficiency |
Comorbidity | C0039538|teratomas |
Sentences | 8 |
PubMedID- 22720040 | The transduction protocol did not affect the pluripotency of the hescs as demonstrated by the expression of pluripotency markers and their ability to form teratomas in nod-scid mice (data not shown). |
PubMedID- 22548356 | Furthermore, cdk2ap2(tr/tr) mescs were unable to form teratomas in severe combined immunodeficiency (scid) mice. |
PubMedID- 20075393 | The vitrified stem cells continued to express markers of pluripotency and formed teratomas in mice with severe combined immunodeficiency, confirming the pluripotency of vitrified-warmed human embryonic stem cell clumps. |
PubMedID- 21284534 | Here we show that the derived cells do not form teratomas in scid mice and independently derived lines show similar patterns of gene expression by microarray analysis. |
PubMedID- 22128806 | However itscs do not form teratomas in severe combined immunodeficient mice. |
PubMedID- 23136396 | Furthermore, ipscs were able to form teratomas in scid mice that contained tissues derived from all three germ layers, including gut-like epithelium (endoderm), cartilage (mesoderm) and neural tissues (ectoderm) (supplementary material fig. |
PubMedID- 21380643 | We reprogrammed primary mouse astrocytes via ectopic retroviral expression of oct3/4, sox2, klf4 and myc and found the ipscs from mouse astrocytes expressed stem cell markers and formed teratomas in scid mice containing derivatives of all three germ layers similar to mouse embryonic stem cells besides semblable morphologies. |
PubMedID- 21565833 | Methods and results: the hipscs generated by episomal vectors generated teratomas in severe combined immunodeficient mice, readily formed embryoid bodies, and differentiated into cardiomyocytes with comparable efficiency to human embryonic stem cells. |
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