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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease severe combined immunodeficiency
Comorbidity C0021400|influenza
Sentences 3
PubMedID- 24204746 P2 (rag1 deficient scid) was transplanted with pre-existing h1n1 influenza colonisation which was resistant to oseltamavir and was requiring ongoing zanamavir therapy.
PubMedID- 20808939 However, as shown previously by others [40], infection of scid mice with a/pr8/34(h1n1) influenza virus followed by passive transfer of two doses of an anti-hemagglutinin antibody cocktail at days 2 and 6 had lead to clearance and full recovery from infection.
PubMedID- 21762748 Lung consolidation in scid mice infected with an influenza a virus is described as plum coloured areas on the lung surface (as we found), which microscopically presents as a proliferative pneumonia, comprising a massive multifocal to coalescing proliferative bronchitis, bronchiolitis, and alveolitis, marked proliferation of type ii pneumocytes, and hyperplastic and hypertrophic columnar epithelium lining the airways [26].

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