eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | severe combined immunodeficiency |
| Comorbidity | C0009319|colitis |
| Sentences | 2 |
| PubMedID- 24189163 | It was previously reported that cd4 t cells from scid mice with colitis proliferate strongly in response to apcs pulsed with fecal extracts 29. α4β7+ and α4β7− cells were thus isolated from the mln and pln of tcrβ-/- mice following naïve t cell transfer, cfse labeled, and cocultured with apcs pulsed with fecal extract ag. |
| PubMedID- 21623559 | Naive t cells were used to induce colitis in mice with severe combined immunodeficiency, which were followed up endoscopically, and a murine endoscopic index of colitis (meic) was developed. |
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