eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | schistosomiasis |
| Comorbidity | C0020541|portal hypertension |
| Sentences | 12 |
| PubMedID- 21358814 | China, splenectomy, either with or without portosystemic anastomosis, is a general surgical intervention for the treatment of portal hypertension due to hepatosplenic schistosomiasis, which would help to reduce the risk of upper gastrointestinal hemorrhage, cure refractory ascites, recover work capacity, and remove hypersplenism [6]. |
| PubMedID- 20332823 | The portal hypertension with hepatosplenic schistosomiasis also plays an important role in the pathogenesis. |
| PubMedID- 26267788 | Conclusion/significance: this study shows that the decrease of flow pressure in portal circulation after splenectomy restores the capacity of hepatocyte synthesis, especially on the factor vii and protein c levels, and these findings suggest that portal hypertension in patients with hepatosplenic schistosomiasis influences liver functioning and the blood coagulation status. |
| PubMedID- 26034376 | We present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia. |
| PubMedID- 25345171 | [efficacy of splenectomy plus selective pericardial devascularization under endoscope in treatment of advanced schistosomiasis patients with portal hypertension and hypersplenism]. |
| PubMedID- 22537571 | Fishermen and peasants in most developing countries like ours work in environment favourable for contracting diseases like schistosomiasis which lead to portal hypertension. |
| PubMedID- 25746428 | The collateral circulation (porto-caval anastomosis) produced by portal hypertension in cases with hepatosplenic schistosomiasis is essential to divert the schistosome and its ova from the portal to the pulmonary vasculature [7,8]. |
| PubMedID- 21912706 | The former is similar to schistosomiasis mansoni and leads to portal hypertension. |
| PubMedID- 22348213 | Moreover, brazilian pathologists have found giant follicular lymphomas in 1577 spleens removed from schistosomiasis mansoni patients with severe portal hypertension (andrade et al., 1971; de andrade et al., 1982). |
| PubMedID- 26078809 | Whether schistosomiasis cirrhosis-induced portal hypertension (sph) model of rabbit or bile duct ligation- (bdl-) or carbon tetrachloride- (ccl4-) induced cirrhosis model of rat, both revealed reduced h2s level in serum and liver tissues by 20% to 80% [13, 20, 38, 41] and decreased cse protein expression by approximately 30% to 80% [13, 20, 38, 43]. |
| PubMedID- 20363433 | Objective: the aim of this study was to describe, for the first time, in a pilot study, the endoscopic aspects of the lesions in the small bowel of patients with portal hypertension due to schistosomiasis, using the pillcam sb, and to determine the usefulness of the method for the diagnosis of esophageal varices. |
| PubMedID- 24255616 | A recent study showed that the levels of thrombopoietin and reticulated platelets werenormal in schistosomiasis patients with portal hypertension and that the bone marrowproduces platelets normally(20). |
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