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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease schistosomiasis
Comorbidity C0020538|hypertension
Sentences 12
PubMedID- 22348213 Moreover, brazilian pathologists have found giant follicular lymphomas in 1577 spleens removed from schistosomiasis mansoni patients with severe portal hypertension (andrade et al., 1971; de andrade et al., 1982).
PubMedID- 25345171 [efficacy of splenectomy plus selective pericardial devascularization under endoscope in treatment of advanced schistosomiasis patients with portal hypertension and hypersplenism].
PubMedID- 21760840 [22] physiopathologic mechanisms of the development of pulmonary arterial hypertension in patients with schistosomiasis is not clearly known, but probably multifactorial.
PubMedID- 20332823 The portal hypertension with hepatosplenic schistosomiasis also plays an important role in the pathogenesis.
PubMedID- 26267788 Conclusion/significance: this study shows that the decrease of flow pressure in portal circulation after splenectomy restores the capacity of hepatocyte synthesis, especially on the factor vii and protein c levels, and these findings suggest that portal hypertension in patients with hepatosplenic schistosomiasis influences liver functioning and the blood coagulation status.
PubMedID- 24255616 A recent study showed that the levels of thrombopoietin and reticulated platelets werenormal in schistosomiasis patients with portal hypertension and that the bone marrowproduces platelets normally(20).
PubMedID- 21358814 China, splenectomy, either with or without portosystemic anastomosis, is a general surgical intervention for the treatment of portal hypertension due to hepatosplenic schistosomiasis, which would help to reduce the risk of upper gastrointestinal hemorrhage, cure refractory ascites, recover work capacity, and remove hypersplenism [6].
PubMedID- 25746428 The collateral circulation (porto-caval anastomosis) produced by portal hypertension in cases with hepatosplenic schistosomiasis is essential to divert the schistosome and its ova from the portal to the pulmonary vasculature [7,8].
PubMedID- 22567478 Significant morbidity is seen in those patients who develop complications such as end-stage renal diseases, chronic liver diseases with portal hypertension, and cancers associated with schistosomiasis [1–3].
PubMedID- 22745835 Two other helminths, schistosoma mansoni and schistosoma japonicum, cause chronic hepatosplenic schistosomiasis, an important cause of pulmonary hypertension and cor pulmonale.
PubMedID- 20363433 Objective: the aim of this study was to describe, for the first time, in a pilot study, the endoscopic aspects of the lesions in the small bowel of patients with portal hypertension due to schistosomiasis, using the pillcam sb, and to determine the usefulness of the method for the diagnosis of esophageal varices.
PubMedID- 26034376 We present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia.

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