eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | sandhoff disease |
| Comorbidity | C0011847|diabetes |
| Sentences | 3 |
| PubMedID- 23977173 | In addition, the fto variant is associated with diabetes-related metabolic traits (including higher fasting insulin, glucose and triglycerides, and lower hdl cholesterol), although the association disappeared after adjustment for bmi [26]. |
| PubMedID- 21294771 | Results: in the 4411 pakistani individuals from this study, the age-, sex- and diabetes-adjusted association of fto variant rs9939609 with bmi was 0.45 (95%ci 0.24-0.67) kg/m(2) per a-allele (p=3.0 x 10(-5) ) and with waist circumference was 0.88 (95% ci 0.36-1.41) cm per a-allele (p=0.001). |
| PubMedID- 24156506 | A recent study in north indian sikhs demonstrated a strong association of fto variants with type 2 diabetes, which did not seem to be mediated through bmi [21]. |
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