eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | rickets |
| Comorbidity | C0020503|secondary hyperparathyroidism |
| Sentences | 4 |
| PubMedID- 24039460 | Although this relationship was not statistically significant following multivariate regression analysis, it is consistent with a large number of studies in different populations and suggests that hypovitaminosis d could lead to secondary hyperparathyroidism, which is harmful to bone health.21,22 it is now well established that vitamin d causes the suppression of pth synthesis by increasing plasma calcium and by acting on parathyroid cells.23,24 in addition, there was a positive correlation between 25(oh)d and hemoglobin and a negative correlation between hemoglobin and pth. |
| PubMedID- 26526462 | Calcitriol concentration also does not reflect the vitamin d reserves, as levels are frequently elevated in individuals with hypovitaminosis d because of secondary hyperparathyroidism. |
| PubMedID- 25284246 | Urinary calcium to creatinine ratio: a potential marker of secondary hyperparathyroidism in patients with vitamin d-dependent rickets type 1a. |
| PubMedID- 26000307 | However, in patients with chronic kidney disease, hypovitaminosis d is frequently associated with secondary hyperparathyroidism which is suppressed by vitamin d supplementation [96]. |
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