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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease rickets
Comorbidity C0020502|hyperparathyroidism
Sentences 4
PubMedID- 25284246 Urinary calcium to creatinine ratio: a potential marker of secondary hyperparathyroidism in patients with vitamin d-dependent rickets type 1a.
PubMedID- 26000307 However, in patients with chronic kidney disease, hypovitaminosis d is frequently associated with secondary hyperparathyroidism which is suppressed by vitamin d supplementation [96].
PubMedID- 26204641 Atypical primary hyperparathyroidism due to hypovitaminosis d.
PubMedID- 24039460 Although this relationship was not statistically significant following multivariate regression analysis, it is consistent with a large number of studies in different populations and suggests that hypovitaminosis d could lead to secondary hyperparathyroidism, which is harmful to bone health.21,22 it is now well established that vitamin d causes the suppression of pth synthesis by increasing plasma calcium and by acting on parathyroid cells.23,24 in addition, there was a positive correlation between 25(oh)d and hemoglobin and a negative correlation between hemoglobin and pth.

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