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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease q fever
Comorbidity C0019158|hepatitis
Sentences 8
PubMedID- 22951661 Fever with hepatitis associated with q fever has rarely been described in the literature.
PubMedID- 19819043 We report a case of severe cholestatic hepatitis due to acute q fever, with clinical signs of hepatic insufficiency, marked cholestasis, and renal insufficiency.
PubMedID- 26485520 C. burnetii causes abortions in domestic ruminants and fever, pneumonia, meningo-encephalitis and hepatitis in acute cases of q fever in humans and endocarditis in chronic cases [2,3].
PubMedID- 24614585 hepatitis due to acute q fever was defined as a >twofold increase in the reference value for alanine aminotransferase (alt; >90 u/l for males, >70 u/l for females) in combination with a >twofold increase in bilirubin (>34 µmol/l).
PubMedID- 22792113 In conclusion, we described a case of chronic q fever with hepatitis and endocarditis that should help clinicians to consider this diagnosis, performing systematically c. burnetii serology, for all patients with heart valve lesions who present with nonspecific symptoms, even if they are apyretic and exhibit no elevation of inflammatory markers.
PubMedID- 20594295 Cases of acute q fever presenting with granulomatous hepatitis and persistent fever in spite of antimicrobial therapy that demanded combination therapy with steroids have been reported [2-4].
PubMedID- 21519168 [q fever as a cause of acute hepatitis accompanying fever].
PubMedID- 20730052 Hyperinflammatory q fever with granulomatous hepatitis and auto-antibodies has been reported in male patients who respond poorly to antimicrobial agents [11].

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