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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease pulmonary arterial hypertension
Comorbidity C0020538|hypertension
Sentences 6
PubMedID- 22086457 Background: candidates for orthotopic liver transplantation (olt) often have porto-pulmonary hypertension (pphtn) with pulmonary arterial hypertension (pah).
PubMedID- 25902784 The dataset was divided into three groups (fig.1): those with normal pulmonary hemodynamics (nph group), those whose hemodynamics met the 5th world symposium on pulmonary hypertension definition of pulmonary arterial hypertension (pah group) (hoeper et al.
PubMedID- 23074643 Associated lesions such as vsd or pda, which increase the left ventricle output, exacerbate the manifestations of mitral inflow obstruction.8 conversely, a supravalvar mitral ring may be difficult to detect in conditions with a diminished pulmonary blood flow such as tetralogy of fallot.9 persistently elevated pulmonary venous hypertension leads to pulmonary arterial hypertension, rise in pulmonary vascular resistance, and eventual failure of the right ventricle and tricuspid regurgitation.
PubMedID- 25223406 Pulmonary hypertension, including pulmonary arterial hypertension (pah), is a serious disease in children, but few clinical studies have been conducted to evaluate treatment regimens in this population.
PubMedID- 22545094 Phenotype labels: interstitial lung disease (ssc-ph-ild), idiopathic arterial hypertension (ipah), scleroderma with pulmonary arterial hypertension (ssc-pah), scleroderma (ssc), pulmonary arterial hypertension only (pah), idiopathic pulmonary fibrosis with pulmonary hypertension (ipf-ph), and human cord blood versus human adult blood (cbvab).
PubMedID- 22482042 Following these encouraging findings, a clinical study was performed to evaluate the short-term safety profile of bay 63-2561 (riociguat) to determine the tolerability and efficacy in patients with moderate to severe pulmonary hypertension (ph) due to pulmonary arterial hypertension, distal chronic thromboembolic ph, or ph with mild to moderate interstitial lung disease [134].

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