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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease psoriasis
Comorbidity C0021053|immune disease
Sentences 5
PubMedID- 22664308 The association of psoriasis with autoimmune diseases.
PubMedID- 24252076 This appears to be unique to psoriasis compared with other autoimmune diseases.
PubMedID- 21110900 In another autoimmune disease of chronic inflammatory skin, psoriasis, il-23/th17 axis is implicated in pathogenesis of the disease [14].
PubMedID- 24550913 Typical autoimmune diseases of the skin are psoriasis, pemphigus vulgaris (pv), and aa; herein, we will not deal with skin specific manifestations of sle which can be considered as a systemic autoimmune disorder with involvement of the skin.
PubMedID- 22754763 However, under inflammatory conditions such as atopic dermatitis and autoimmune disease of the skin (psoriasis, lichen planus and pemphigus vulgaris) nk cells are recruited in large numbers to skin lesions43 and could infrequently be seen in direct contact with dcs.44,45 nk cells are found to deeply penetrate non-vascularized epidermis which contains langerhans cells, demonstrating their ability to move and migrate through dense, solid tissue toward an inflamed locus containing dc.45 therefore, the recruitment of nk cells to an inflamed skin lesion can occur from both the peripheral blood and the dermal pool of nk cells.

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