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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease psoriasis
Comorbidity C0020538|hypertension
Sentences 10
PubMedID- 23800996 Ambulatory blood pressure monitoring can unmask hypertension in patients with psoriasis vulgaris.
PubMedID- 25588781 Many studies conducted in western and asian countries have reported that the prevalence and incidence of the risk factors for myocardial infarction and stroke such as diabetes mellitus, hyperlipidaemia and hypertension, are high in patients with psoriasis, particularly those with severe psoriasis.16–19 the reasons why these risk factors are increased in patients with psoriasis have not been fully explained, but the increased risk may be due to the high prevalence of obesity and other known predisposing factors in patients with psoriasis.20 it is also possible that some of the comorbidities are adverse reactions to ciclosporin and other systematic therapies for psoriasis.21 in our study, an increase in comorbidity was observed in patients with severe psoriasis but not in patients with severe ppp when compared to patients receiving topical therapy only.
PubMedID- 24584739 Sensitivity analyses excluding psoriasis patients with hypertension and taking anti‐hypertensive medication, with hyperlipidemia and taking lipid‐lowering medication, with diabetes, and who were active smokers were also performed.
PubMedID- 21569114 In a multivariate analysis, hypertension was associated with psoriasis after controlling for age, gender, diabetes, obesity and smoking (or = 1.44, 95% confidence interval: 1.07-1.94).
PubMedID- 23112353 There was no difference in the high density lipoprotein (hdl) levels and presence of hypertension among patients with psoriasis and normal controls.
PubMedID- 23249828 On the basis of random effects modeling of case-control and cross-sectional studies, the odds ratio (or) for hypertension among patients with psoriasis was 1.58 [95% confidence interval (ci) 1.42-1.76] compared with the controls.
PubMedID- 25673933 In particular, it has been well established that the prevalence of cv diseases and conventional cv risk factors, such as obesity, smoking, diabetes mellitus, hyperlipidemia, and hypertension, is higher in patients with psoriasis than in the general population5,6,7,8.
PubMedID- 22654590 In our study we observed that psoriasis is associated with smoking, dm, hypertension, and ms. dm and hypertension was accompanying our psoriasis patients along with ms. these findings confirmed the literature [3, 11, 13, 14].
PubMedID- 20107721 In a multivariate analysis, hypertension was associated with psoriasis after controlling for age, sex, smoking status, obesity, diabetes, non-steroidal anti-inflammatory drugs (nsaids) and use of cox-2 inhibitors (odds ratio: 1.37, 95% confidence interval: 1.29-1.46).
PubMedID- 23134418 Conclusions: psoriasis is strongly associated with hypertension, diabetes mellitus and obesity.

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