eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | psoriasis |
| Comorbidity | C0011570|depression |
| Sentences | 19 |
| PubMedID- 20015170 | The relationship of psoriasis with psychiatric morbidities (depression, stress-related disorders, behaviour disorders and schizophrenic disorders), cardiovascular risk factors (diabetes, hypertension, obesity and dyslipidaemia) and cardiovascular events [myocardial infarction (mi), stroke] was investigated using logistic and linear regression models. |
| PubMedID- 24082881 | In addition to its cutaneous manifestations, psoriasis has been associated with inflammatory arthritis, depression, anger, anxiety, frustration, and considerable health-related quality of life impairment, which appear independent of objective disease severity [4, 5]. |
| PubMedID- 25856968 | The prevalence of depression in patients with psoriasis is estimated between 10 % and 62 % according to different studies. |
| PubMedID- 22844272 | 's study showed that the magnitude of anxiety and depression in patients with psoriasis is higher than that in healthy individuals, but they found no association between severities of psoriasis with anxiety [14], whereas harvima et al. |
| PubMedID- 24934916 | Suicide and depression in a patient with psoriasis receiving adalimumab: the role of the dermatologist. |
| PubMedID- 25672294 | Evidence shows an association of psoriasis with arthritis, depression, inflammatory bowel disease and cardiovascular diseases. |
| PubMedID- 26086213 | This study examined the risk of new-onset depression in patients with psoriasis in a nationwide danish cohort including some 5 million people in the period 2001-2011. |
| PubMedID- 26186277 | Objectives: in this prospective cohort study, we investigated the risk of incident depression among individuals with psoriasis and psoriatic arthritis (psa). |
| PubMedID- 24003268 | Kurd et al.24 reported that the adjusted hazard ratio for receiving a diagnosis of depression in patients with psoriasis, when compared with the respective control population, was 1.31 (95% confidence interval, 1.37~1.41). |
| PubMedID- 24284419 | The reported prevalence of depression in psoriasis varies substantially. |
| PubMedID- 26421371 | Conclusions and relevance: self-reported history of psoriasis was independently associated with major depression as assessed by a validated screening tool, even when controlling for comorbidities. |
| PubMedID- 25781210 | Irs per 1000 patient-years of af were 3.21, 5.02, 8.41, 5.39 and 7.41; and irs of stroke were 2.62, 3.09, 6.71, 3.62 and 9.03 for the reference population, mild psoriasis without depression, mild psoriasis with depression, severe psoriasis without depression and severe psoriasis with depression, respectively. |
| PubMedID- 26280176 | psoriasis is associated with depression, myocardial infarction (mi) and stroke. |
| PubMedID- 26550011 | Exacerbation of psoriasis with worsening depression and anxiety is common, and a variety of physiological pathways may be involved in mediating this relationship. |
| PubMedID- 25556559 | Early onset psoriasis is associated with depression, social discrimination, and greater lt dlqi. |
| PubMedID- 23374943 | When adjusting for age, bmi, gender, and depression, those with psoriasis were not more likely to experience poor sleep quality (p=0.25), nor to score in a higher insomnia category (p=0.20) or be more "sleepy" (p=0.53). |
| PubMedID- 24459298 | psoriasis is independently associated with depression, psoriasis patients are twice as likely to have suicidal thoughts compared with the general population and people with chronic illnesses. |
| PubMedID- 24372845 | The hazard ratio for depression in psoriasis patients vs. the general population is about 1.4–1.5 and increases with severity of psoriasis.20,21 depression is reported in 15–62% of patients (table 1),21,22 and suicidal ideation is reported in 5.5% to 9.7% of psoriasis patients.23 other psychiatric diagnoses are also common.19 psychiatric symptoms are associated with reduced quality of life in psoriasis patients.24,25 alcohol abuse is reported in 15–30% of psoriasis patients.26–29 there is little evidence for an association between alcohol consumption and severity of psoriasis, but excess alcohol consumption appears to be associated with depression in psoriasis patients,26,28 and may adversely affect treatment outcomes, particularly regarding poor compliance.28 psoriasis patients have an increased likelihood of smoking compared with the general population, with odds ratios from 1.31 to 2.96 reported.30–32 smoking is also associated with psoriasis disease severity,29,32 and is correlated with impaired psoriasis-related quality of life.33 all of these addictive behaviours may be related to the emotional burden of the psoriasis patient having a stigmatising disease. |
| PubMedID- 25520742 | The aim of this study was to examine the prevalence of alexithymia and its association with anxiety and depression in patients with psoriasis compared with healthy participants, while taking into consideration demographic and clinical variables. |
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