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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease psoriasis
Comorbidity C0004153|atherosclerosis
Sentences 8
PubMedID- 21039409 Background: psoriasis is associated with premature atherosclerosis although the underlying mechanism remains unclear.
PubMedID- 23448140 Objectives: to determine the presence of subclinical atherosclerosis in patients with psoriasis (without overt cardiovascular complications or traditional cardiovascular disease risk factors), compared with controls.
PubMedID- 21547343 Results from case-control studies of endothelial dysfunction, a marker of early atherosclerosis, in patients with moderate-to-severe psoriasis have been conflicting and were conducted with operator-dependent and technically demanding ultrasound measurement of brachial artery flow-mediated vasodilation.
PubMedID- 20827428 Several lines of evidence indicated that psoriasis is associated with enhanced atherosclerosis and risk of cardiovascular disease, and inflammation is a pivotal link between psoriasis and atherosclerosis 17, 18.
PubMedID- 23492918 psoriasis is not associated with atherosclerosis and incident cardiovascular events: the rotterdam study.
PubMedID- 23003220 However, the prevalence and extent of atherosclerosis in patients with psoriasis are unknown.
PubMedID- 26100340 atherosclerosis together with multiple sclerosis, psoriasis and rheumatoid arthritis can be used as examples of chronic inflammatory diseases associated with multifactorial components that evolve over the years.
PubMedID- 21233693 They also describe the potential pathways believed to link psoriasis with atherosclerosis and the role of hyperlipidemia therapy in this setting.

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