eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | precocious puberty |
| Comorbidity | C0028754|obesity |
| Sentences | 5 |
| PubMedID- 20088734 | Childhood obesity is associated with early onset of puberty, menstrual irregularities during adolescence and polycystic ovary syndrome. |
| PubMedID- 22984508 | Nutritional conditions play important roles in regulating the timing of entry into puberty: malnutrition delays the onset of puberty and obesity leads to precocious puberty [44], [45], [46]. |
| PubMedID- 24904857 | Further studies are needed to reveal the relationship between sex hormone and obesity in girls with precocious puberty. |
| PubMedID- 23752155 | Although obesity has been associated with precocious puberty, whether children with blount disease have advanced skeletal maturity has not been previously investigated. |
| PubMedID- 26060666 | Several studies indicate that the childhood obesity is a predictor of early puberty (20). |
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