eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | pre-eclampsia |
| Comorbidity | C0033687|proteinuria |
| Sentences | 14 |
| PubMedID- 26405111 | In conclusion, therapeutic apheresis reduced circulating sflt-1 and proteinuria in women with very preterm preeclampsia and appeared to prolong pregnancy without major adverse maternal or fetal consequences. |
| PubMedID- 23554789 | Hypertensive disorders during pregnancy were divided into three specific subtypes: 1) gestational hypertension (blood pressure < 140/90 mmhg without proteinuria after 20 weeks of gestation); 2) mild preeclampsia (blood pressure ≥ 140/90 mmhg with proteinuria of 1+ on dipstick in two samples taken 6 h apart or > 300 mg in a 24 h urine collection); 3) severe preeclampsia (blood pressure ≥ 160/110 mmhg with proteinuria of 2+ on the dipstick in two samples taken 6 h apart or > 2 g total protein within a 24 hous urine collection). |
| PubMedID- 25628644 | Nevertheless, preeclampsia (i.e., hypertension with proteinuria) is a major cause of both maternal and fetal mortality and morbidity (haig, 1993). |
| PubMedID- 25693057 | We report here that all at1-aa-positive hypertensive pregnant women exhibited decreased aldosterone levels, and early-onset preeclampsia patients with high proteinuria showed an inverse correlation of aldosterone levels with at1-aa. |
| PubMedID- 24130940 | New onset of hypertension and doubling 24-h urinary proteins or urine/creatinine ratio after 20th week of pregnancy was considered superimposed preeclampsia in those with proteinuria >300 mg/day and no hypertension at baseline. |
| PubMedID- 25995814 | preeclampsia is characterized with hypertension and proteinuria during pregnancy, and can have serious consequences about maternal and fetal health. |
| PubMedID- 20385595 | Placental overproduction of sflt1 may contribute to the syndrome of preeclampsia with proteinuria and hypertension since recombinant sflt1 induces proteinuria in pregnant and non-pregnant rodents (6–8). |
| PubMedID- 24779244 | Conclusion: the authors concluded that proteinuria in patients with preeclampsia is associated with adverse outcome in pregnancy, although it is not an adequate predictor. |
| PubMedID- 25181538 | Low molecular weight heparin improves proteinuria in rats with l-name induced preeclampsia by decreasing the expression of nephrin, but not podocin. |
| PubMedID- 24712704 | Post-partum trend in blood pressure levels, renal function and proteinuria in women with severe preeclampsia and eclampsia in sub-saharan africa: a 6-months cohort study. |
| PubMedID- 22384039 | preeclampsia (with documented proteinuria and edema) was reported in 18% of women, and eclampsia in 3%, and these did not differ by hiv status. |
| PubMedID- 24551572 | preeclampsia is manifested with hypertension, proteinuria, and edema. |
| PubMedID- 21808734 | Reported that proteinuria in patients with preeclampsia is associated with downregulation of podocyte foot process proteins, as nephrin and synaptopodin [101]. |
| PubMedID- 24883213 | Characterized by the core symptoms hypertension and proteinuria after 20 weeks of gestation, preeclampsia is a leading cause of maternal and fetal morbidity and mortality [227]. |
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