eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | pre-eclampsia |
| Comorbidity | C0022116|ischemia |
| Sentences | 3 |
| PubMedID- 24159378 | Hypertension in preeclampsia is associated with placental ischemia-induced release of antiangiogenic soluble fms-like tyrosine kinase (sflt-1) into the maternal circulation, which antagonizes vascular endothelial growth factor (vegf) promoting endothelial dysfunction. |
| PubMedID- 22195275 | We have recently demonstrated that induction of the ho-1 pathway could significantly attenuate the preeclampsia-like pathological manifestations associated with experimental placental ischemia in the rodent. |
| PubMedID- 26444006 | These data suggest that preeclampsia associated with placental ischemia and late hypoxic events may be responsible for the diminished content of placental aromatase observed in preeclamptic patients. |
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