eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | portal hypertension |
| Comorbidity | C0023890|cirrhosis |
| Sentences | 135 |
| PubMedID- 23812828 | Histopathological evaluation remains critical in excluding cirrhosis and other causes of portal hypertension, and is the only way of definitively establishing the diagnosis of opv. |
| PubMedID- 21827004 | Reconstructed cta images showed that different collateral vessels were developed at the end-stage of chronic liver cirrhosis due to severe portal hypertension. |
| PubMedID- 25812120 | In some patients liver fibrosis leads to liver cirrhosis with portal hypertension, hepatocellular dysfunction and increased risk of hepatocellular carcinoma [2,3]. |
| PubMedID- 24974920 | Evaluation of cardiac systolic and diastolic functions in liver cirrhosis patients with portal hypertension conventional was done by conventional doppler echocardiography and tdi. |
| PubMedID- 21223822 | Methods: the rats of hepatic cirrhosis with portal hypertension were randomly assigned into 1 control group, 1 model group and 4 treatment groups (ns, hgf, ins, hgf + ins). |
| PubMedID- 25793622 | Blockade of nitric oxide during perfusion of the hepatic arteries in cirrhosis with portal hypertension corrects the vasoconstrictive response to normal. |
| PubMedID- 21904911 | In contrast, animals from group 4 (pvs + taa) showed well-developed micronodular and macronodular cirrhosis, associated with significant portal hypertension and hypersplenism. |
| PubMedID- 25701619 | Objective: we have compared the influences of three surgical strategies on the occurrence and development of portal vein thrombosis (pvt) in patients with liver cirrhosis complicated by portal hypertension (pht) in this study. |
| PubMedID- 21801303 | Currently, nothing is known about isoform-specific characteristics in cirrhosis with portal hypertension, including any information as to which isoform is up-regulated/down-regulated. |
| PubMedID- 22334252 | Development of ascites in compensated cirrhosis with severe portal hypertension treated with beta-blockers. |
| PubMedID- 20500867 | • childs b or c cirrhosis or with evidence of severe portal hypertension by history, endoscopy, or radiologic studies or with evidence of moderate to severe ascites. |
| PubMedID- 20921950 | portal hypertension in cirrhosis depends on increased intrahepatic vascular resistance, which is explained by fibrosis and intrahepatic hyperresponsiveness to vasoconstrictors. |
| PubMedID- 25013336 | Ehpvo has a unique clinical profile, which differentiates it from portal hypertension associated with cirrhosis of the liver. |
| PubMedID- 20653965 | Patent paraumbilical and abdominal subcutaneous veins are found frequently as collaterals in patients due to portal hypertension, mainly associated with liver cirrhosis [1,2]. |
| PubMedID- 25038804 | Estimation of the severity of portal hypertension in patients with liver cirrhosis is another major use of liver stiffness measurements. |
| PubMedID- 21506350 | An analysis of 115 liver cirrhosis patients with portal hypertension was made to find out which of them had variceal bleeding and high risk of its development. |
| PubMedID- 21843735 | Patients with recurrent complications or cirrhosis may die because of recurrent infection, portal hypertension, liver failure, or cholangiocarcinoma. |
| PubMedID- 26406236 | Background & aims: although in cirrhosis with portal hypertension levels of the vasoconstrictor angiotensin ii are increased, this is accompanied by increased production of angiotensin (ang)-(1-7), the endogenous ligand of the mas receptor (masr), which blunts hepatic fibrosis and decreases hepatic vascular resistance. |
| PubMedID- 24171010 | Table 1 summarizes the hepatobiliary clinical findings in cf.the evolution of cfld is usually slow and progressive: only about 10% of patients affected by cf and cirrhosis with portal hypertension progress to liver synthetic failure generally after pediatric age (14, 43, 44). |
| PubMedID- 23831908 | The natural history of cirrhotic patients is highly variable due to several factors including hepatic synthetic function, presence and degree of portal hypertension, the cause of cirrhosis, the possibility of resolution of the underlying damaging process, and the occurrence of liver cancer. |
| PubMedID- 26064107 | They can detect advanced cirrhosis with signs of portal hypertension (enlarged spleen and portal vein, and collateral venous circulation), but not fibrosis of lesser stages [76, 77]. |
| PubMedID- 21423905 | Color doppler evaluation of left gastric vein hemodynamics in cirrhosis with portal hypertension and its correlation with esophageal varices and variceal bleed. |
| PubMedID- 25658710 | However, advanced liver disease, defined as multilobular cirrhosis frequently with portal hypertension, occurs in only 5–10% of individuals with cf [4,5,7]. |
| PubMedID- 25256370 | Background: decreased antithrombin iii (atiii) activity and large splenic vein diameter (svd) are risk factors for portal vein thrombosis (pvt) after splenectomy in liver cirrhosis with portal hypertension. |
| PubMedID- 21705304 | A detailed interview and examination by occupational health and other medical specialists revealed that the patient had been suffering from wilson's disease from the age of 13, and had now developed hepatic manifestations (compensated liver cirrhosis with portal hypertension), neurological manifestations (dystonia, dysarthria, muscle weakness, vertigo), and psychiatric manifestations (depression, insomnia, cognitive impairment) of the disease, including problems partially caused by long-lasting treatment with copper chelating agents (neurological and haematological manifestations). |
| PubMedID- 25356325 | Resultant complications included compensated cirrhosis with portal hypertension, oesophageal varices and a previous episode of culture-negative sbp. |
| PubMedID- 25539572 | Most portal hypertension results from cirrhosis but extra hepatic portal vein obstruction is the single commonest cause. |
| PubMedID- 24673975 | Thrombocytopenia: in time, liver cirrhosis leads to portal hypertension. |
| PubMedID- 20951924 | This article reviews the pathophysiologic bases of the different pharmacologic treatments for portal hypertension in patients with cirrhosis and places them in the context of the natural history of varices and variceal hemorrhage. |
| PubMedID- 20583425 | Background/aims: endosonography (eus) is rarely used in the routine diagnostic of portal hypertension in patients with cirrhosis even though it has significantly higher sensitivity for detection of varices than gastroduodenoscopy. |
| PubMedID- 24820919 | Case background: ascites appears mainly as a consequence of portal hypertension in patients with liver cirrhosis, or can be caused by several other causes, such us congestive heart failure, peritoneal malignancy, or tuberculosis. |
| PubMedID- 25933224 | Liver cirrhosis with portal hypertension is characterized by systemic and splanchnic vasodilatory substances release, especially nitric oxide (no) and prostacyclin [3], which lead to hyperdynamic circulatory status, and further increased mesenteric blood flow and portal inflow. |
| PubMedID- 25834800 | If liver fibrosis progress to cirrhosis, complications arising from portal hypertension and functional hepatocyte loss develop. |
| PubMedID- 24829653 | However the normal platelet count and serum albumin in the patient is not in favor of advanced cirrhosis as the cause of portal hypertension. |
| PubMedID- 25655526 | cirrhosis in pregnancy with concomitant portal hypertension or esophageal varices is rare. |
| PubMedID- 26058680 | Bacterial translocation is associated with portal hypertension in cirrhosis but this is almost unexplored in hepatosplenic schistosomiasis. |
| PubMedID- 25798930 | Objective: to investigate the role of contrast-enhanced ultrasonography (ceus) and doppler ultrasonography (dus) in the diagnosis of severe portal hypertension (ph) in patients with liver cirrhosis (lc). |
| PubMedID- 22697282 | The performed magnetic resonance imaging examination confirmed the diagnosis of cirrhosis associated with portal hypertension and detected a vascular left transdiaphragmatic hernia. |
| PubMedID- 25709491 | It has been identified as one of the leading causes of mortality, with close to 50,000 deaths attributed to it per year in the united states.1 the major morbidity from cirrhosis is due to portal hypertension, with formation of venous collaterals and marked circulatory as well as vascular abnormalities. |
| PubMedID- 21103219 | Psc is characterized by progressive periductal obliterating fibrosis and strictures in the intrahepatic and extrahepatic bile ducts and usually follows a progressive course leading to cirrhosis with complications of portal hypertension and end-stage liver failure [1]. |
| PubMedID- 23670970 | The greater hazard ratio (hr) for liver disease in the gms than in cgs and tss (whose hrs did not differ; p = 0.9) is attributed to the stringent criteria for liver disease (i.e., presence of portal hypertension attributable to cirrhosis). |
| PubMedID- 26422126 | Development of hyperdynamic circulation and response to beta-blockers in compensated cirrhosis with portal hypertension. |
| PubMedID- 22034603 | [1] pah is also an uncommon but documented complication of hiv infection, chronic hemolytic anemia, and cirrhosis with portal hypertension. |
| PubMedID- 25848466 | The treatment of cirrhosis-induced portal hypertension in children and adolescents is mostly based on methods developed for adults. |
| PubMedID- 25393320 | Complications of portal hypertension were significantly associated with cirrhosis (p<0.001) rather than with the severity of pvt and presence of cavernoma. |
| PubMedID- 22848732 | Diagnosis of cfld is challenging because its clinical presentation ranges from simple steatosis to multi-lobular biliary cirrhosis with portal hypertension [2], [3]. |
| PubMedID- 23755897 | Propranolol treatment of portal hypertension in cirrhosis patients is better the higher the untreated pressure: a single-centre prospective experience. |
| PubMedID- 24697006 | In second pregnancy, medically induced abortion was performed in the 12th week because of deterioration of the underlying disease, liver cirrhosis with portal hypertension. |
| PubMedID- 22009385 | Background: portal hypertension associated with liver cirrhosis increases the risk of postoperative complications after liver resection for hepatocellular carcinoma (hcc). |
| PubMedID- 24949616 | Partial splenic embolization is an effective interventional procedure performed in liver cirrhosis complicated with portal hypertension to improve the low platelet count. |