eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | polycystic ovary syndrome |
| Comorbidity | C0021359|infertility |
| Sentences | 59 |
| PubMedID- 24586979 | It remains unclear whether the observed sexual dimorphism is due to ivm technology or to maternal characteristics such as underlying infertility in patients with polycystic ovary syndrome (pcos). |
| PubMedID- 25879641 | We performed a double-blind multi-center controlled trial, testing letrozole versus clomiphene for infertility in women with polycystic ovary syndrome. |
| PubMedID- 23182556 | The ovulatory infertility associated with pcos can be overcome in most cases with oral (clomiphene citrate or letrozole) or injectable (gonadotropins) agents. |
| PubMedID- 25859492 | Those who had pcos but were associated with male factor infertility, deep infiltrating endometriosis and submucous fibroids were excluded. |
| PubMedID- 25566617 | Objective: to study the effect and potential mechanism of modified cangfu daotan decoction (mcdd) on endometrial receptivity in infertility patients with polycystic ovarian syndrome (pcos). |
| PubMedID- 25493168 | Background: nitric oxide (no) involves in polycystic ovary syndrome (pcos), a cause of infertility in women during the reproductive age. |
| PubMedID- 21547497 | These include: prevention of chronic obstructive pulmonary disease exacerbation, attenuation of illness from the influenza virus, treatment of pulmonary fibrosis and treatment of infertility in patients with clomifene-resistant polycystic ovary syndrome [50]. |
| PubMedID- 20980683 | Metformin is an insulin sensitizer molecule used for the treatment of infertility in women with polycystic ovary syndrome and insulin resistance. |
| PubMedID- 22357073 | One of the first suggested treatments for infertility associated with pcos is weight reduction, which has been shown to increase the chance of spontaneous ovulation and menstruation. |
| PubMedID- 21839435 | Patient(s): a 26-year-old patient with a history of primary infertility due to polycystic ovary syndrome (pcos) presented with acute pelvic pain after transvaginal ultrasound-guided oocyte retrieval for in vitro fertilization-embryo transfer. |
| PubMedID- 22128296 | Background: clomifene citrate (cc) is accepted as the first-line method for ovulation induction (oi) in patients with polycystic ovary syndrome (pcos) associated with infertility owing to anovulation. |
| PubMedID- 20222840 | Objective: the aim of this study was to compare the effectiveness of myo-inositol (myo) and metformin, in monotherapy or in association with recombinant follicle stimulating hormone (r-fsh), in the treatment of menstrual irregularities, chronic anovulation, and female infertility in patients with polycystic ovary syndrome (pcos). |
| PubMedID- 22488491 | [use of insulin sensitizers in the treatment of infertility in patients with polycystic ovary syndrome (pos)]. |
| PubMedID- 24273971 | Conclusions: dxp could improve the ovulation rate and the pregnancy rate in anovulation infertility patients with pcos complicated ir. |
| PubMedID- 25554522 | Background: infertility associated with polycystic ovary syndrome (pcos) could be related to many mechanisms including endometrial factors. |
| PubMedID- 21688169 | Co-involvement of psychological and neurological abnormalities in infertility with polycystic ovarian syndrome. |
| PubMedID- 22781109 | Objective: to compare clinical and laboratory outcomes of in vitro maturation (ivm) with in vitro fertilization-embryo transfer (ivf-et) in treatment of infertility associated with polycystic ovary syndrome (pcos). |
| PubMedID- 25874409 | In addition to irregular menses, hirsutism and infertility, women with pcos may display a number of metabolic and cardiovascular abnormalities [3, 11–13] and several psychological disorders such as depression, anxiety, marital and social problems and sexual functioning impairment [14–16]. |
| PubMedID- 25550522 | Polycystic ovarian syndrome (pcos), the leading cause of female infertility, is associated with an increase in luteinizing hormone (lh) pulse frequency, implicating abnormal steroid hormone feedback to gonadotropin-releasing hormone (gnrh) neurons. |
| PubMedID- 22523872 | Does assisted reproductive technology itself or polycystic ovary syndrome as a cause of infertility have any effect on first trimester serum screening results. |
| PubMedID- 20865044 | polycystic ovary syndrome (pcos), the leading cause of anovulatory infertility among premenopausal women, is now essentially known as androgen excess disorder [1]. |
| PubMedID- 21297382 | Benefit is also evident when acupuncture is performed for female infertility due to polycystic ovary syndrome (pcos). |
| PubMedID- 24639732 | Conclusion: infertility among women with pcos was not a consequence of changes in leptin concentrations. |
| PubMedID- 22431566 | Conclusions: in the absence of supportive high-quality evidence, ais should not be recommended as the first-line pharmacological therapy for infertility in women with pcos, and further research is needed. |
| PubMedID- 21466513 | Background: there are differences in opinion as to whether metformin should play a role in the primary treatment of anovulatory infertility for women with polycystic ovary syndrome (pcos). |
| PubMedID- 24995944 | Logistic regression analysis showed that pcos women with infertility have a significantly lower sexual function score compared with those who are fertile. |
| PubMedID- 22554175 | Evidence-based lifestyle and pharmacological management of infertility in women with polycystic ovary syndrome. |
| PubMedID- 21306326 | Timed intercourse with clomiphene citrate as a first-line treatment for anovulatory infertility associated with polycystic ovary syndrome. |
| PubMedID- 24362411 | It is also useful in the management of anovulatory infertility in women with pcos who have a bmi within the normal range. |
| PubMedID- 24282248 | Letrozole, berberine, or their combination for anovulatory infertility in women with polycystic ovary syndrome: study design of a double-blind randomised controlled trial. |
| PubMedID- 24014601 | For women attending an infertility clinic, those with diagnosed polycystic ovarian syndrome indicated significantly (p < 0.0005) greater circulating insl3 levels and those with low ovarian reserve showed significantly (p < 0.002) decreased insl3 values. |
| PubMedID- 23359971 | Methods: forty infertility patients with clomiphene-resistant pcos were assigned to two groups using stratified random sampling method according to age, infertility time, and body mass index, 20 in each group. |
| PubMedID- 20639519 | Therefore, it is hypothesized that a disruption in the regulatory mechanisms of egf synthesis and/or physiological function mediated by egfr may cause anovulatory infertility in women with pcos (almahbobi and trounson, 1996; almahbobi et al., 1998). |
| PubMedID- 22723725 | Incorporating patient preference into the management of infertility in women with polycystic ovary syndrome. |
| PubMedID- 24669621 | Background: anovulatory infertility due to polycystic ovarian syndrome (pcos) remains the commonest cause among women of reproductive age group. |
| PubMedID- 24505354 | It is a leading cause of female infertility and is associated with polycystic ovaries, hirsutism, obesity, and insulin resistance [1], [2]. |
| PubMedID- 24458485 | Literature data indicate that the infertility in women with polycystic ovary syndrome (pcos) is not only attributed to anovulation but also to endometrial dysfunction. |
| PubMedID- 22419702 | Background: the role of metformin in the treatment of infertility in women with polycystic ovary syndrome (pcos) is still controversial. |
| PubMedID- 21511534 | It is concluded that ovarian drilling is an option in the management of female infertility associated with pcos, especially as a second-line treatment after the failure of clomiphene citrate treatment. |
| PubMedID- 25653680 | pcos is mainly associated with anovulation, infertility, insulin resistance, and hyperandrogenism leading to metabolic disorders such as diabetes and cardiovascular diseases [4–6]. |
| PubMedID- 23977313 | Increased activity of the sympathetic nerves can promote polycystic ovary syndrome, a major cause of infertility [20,21]. |
| PubMedID- 25393639 | Context: polycystic ovary syndrome (pcos), a major cause of anovulatory infertility, is characterized by arrested follicular growth. |
| PubMedID- 24145507 | Polycystic ovarian disease (pcod) is an endocrine disorder characterised by bilateral polycystic ovaries, anovulation leading to infertility, irregular menstrual cycles and features of androgen hormone excess. |
| PubMedID- 22554176 | Evidence-based management of infertility in women with polycystic ovary syndrome using surgery or assisted reproductive technology. |
| PubMedID- 20394912 | Treatment of infertility in women with polycystic ovary syndrome. |
| PubMedID- 24023577 | In addition to irregular menses, hirsutism, and infertility, women with pcos may display a number of metabolic abnormalities including hyperinsulinemia, insulin resistance, dyslipidemia, and obesity [2]. |
| PubMedID- 21283731 | In addition to the primary features of hyperandrogenemia, chronic anovulation and infertility, women with pcos are also at increased risk for obesity, insulin resistance and type 2 diabetes. |
| PubMedID- 21631446 | Analysis of factors predicting success of metformin and clomiphene treatment for women with infertility owing to pcos-related ovulation dysfunction in a randomised controlled trial. |
| PubMedID- 23141287 | [therapeutic effect of metformin for clomiphene-resistant infertility patients with polycystic ovary syndrome: a systematic analysis]. |
| PubMedID- 22279474 | Other studies are needed to evaluate correlation between psa level and prognosis of pcos in infertility and metabolic disorder. |
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