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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease polycystic ovary syndrome
Comorbidity C0020538|hypertension
Sentences 14
PubMedID- 21565677 The increased prevalence of hypertension in women with polycystic ovary syndrome (pcos) may contribute to the increased risk of cardiovascular disease in these women.
PubMedID- 24278732 The purpose of this study is to re-evaluate whether the prevalence of polycystic ovary syndrome (pcos) amongst women with idiopathic intracranial hypertension (iih) is higher than in the general population using the nih criteria.
PubMedID- 24368020 Objective: to determine the prevalence of hypertension in women with polycystic ovary syndrome (pcos).
PubMedID- 23978544 hypertension associated with pregnancy and polycystic ovary syndrome is unique to women.
PubMedID- 23926485 Several of these features increase the risk of cardiovascular diseases (cvd) in women (3) and the prevalence of hypertension in women with pcos is about 40% in comparison with a prevalence of about 25.8 in the general population (4).
PubMedID- 24379699 Potential mechanisms of hypertension in pcos include endothelial dysfunction, as evidenced by increased endothelin-1 levels80 and increased aldosterone concentrations related to insulin resistance.81 however, many of these studies did not control for obesity; a common comorbidity in pcos and a well-known risk factor for hypertension.82 lo et al reported that women with pcos were more likely to have hypertension or elevated blood pressure than controls after adjusting for bmi category, age, diabetes, and dyslipidemia (adjusted or 1.53, 95% ci 1.31–1.51).83 czech women with pcos were also more likely to have hypertension compared to controls.84 hypertension was present in 22% of the women with pcos compared to 2.1% of controls.
PubMedID- 24371816 [23] reported that hyperandrogenemia in young women with pcos was associated with hypertension, independent of insulin resistance, age, or obesity.
PubMedID- 24894925 Idiopathic intracranial hypertension associated with polycystic ovarian syndrome.
PubMedID- 25878664 Cut-off value 1.10 had sen: 82.4% and sp: 72.7% for prediction of hypertension in pcos ≥30 years.
PubMedID- 22934032 A recent case report in two obese pcos patients with hypertension showed that renal denervation exerted beneficial effects not only on blood pressure control but also on insulin resistance, renal, and endocrine abnormalities characteristic of pcos (schlaich et al., 2011).
PubMedID- 26508882 Furthermore, several studies have suggested that there is an increased prevalence of hypertension among women with pcos compared to the general population, irrespective of their weight.52–54 on the other hand, luque-ramírez et al55 support the view that high blood pressure is only observed among overweight and obese women with pcos.
PubMedID- 24829525 ), the exact mechanisms responsible for hypertension in women with pcos are yet to be clarified.
PubMedID- 21536229 The mechanisms responsible for hypertension in women with pcos have not been elucidated.
PubMedID- 22882204 Renal sympathetic denervation also reduced msna, noradrenaline spillover and blood pressure in two pcos subjects with hypertension, accompanied by improved insulin sensitivity.

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