eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | placental insufficiency |
| Comorbidity | C0040053|thrombosis |
| Sentences | 1 |
| PubMedID- 21429808 | It is hypothesised that thrombophilias may increase the risk of placental insufficiency because of placental micro-vascular thrombosis, macro-vascular thrombosis, or both, as well as effects on trophoblast growth and differentiation.17 abnormalities of the clotting cascade are well documented in women with pre-eclampsia.18 the endothelial damage of pre-eclampsia is associated with an altered phenotype from anticoagulant to procoagulant and decreased endothelially mediated vasorelaxation. |
Page: 1