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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease placental insufficiency
Comorbidity C0032914|preeclampsia
Sentences 4
PubMedID- 19562524 The clinical features include recurrent abortions at various stages, including implantation, placentation in the first trimester, miscarriages in the second and third trimesters, intrauterine growth retardation, preeclampsia with placental insufficiency and growth restrictions, arterial and venous thrombosis, and possibly also infertility.
PubMedID- 24362545 preeclampsia may be associated with placental insufficiency and maternal organ dysfunction.
PubMedID- 25118501 The presence or absence of placental insufficiency in pregnancy complicated by preeclampsia seems to determine the clinical course of the disease, thus allowing for an alternative classification of the condition into placental and maternal preeclampsia.
PubMedID- 26241326 Conclusions: the effects of high glucose on exosomes bioactivity may be recapitulated in vivo and is of clinical relevance in association with maternal insulin resistance (resulting in hyperglycemia) and preeclampsia (associated with placental insufficiency and hypoxia).

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