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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease peripheral t-cell lymphoma
Comorbidity C0024299|lymphoma
Sentences 6
PubMedID- 21045384 Background: angioimmunoblastic t-cell lymphoma (aitl), a subtype of peripheral t-cell lymphoma (ptcl), is characterized by unique clinical and biological features.
PubMedID- 24756092 140 t-cell lymphomas consisted of peripheral t-cell lymphoma-unspecified, extranodal natural killer cell/t-cell lymphoma, anaplastic large cell lymphoma, angioimmunoblastic t-cell lymphoma, t-cell type lymphoblastic lymphoma and cutaneous t-cell nhl.
PubMedID- 21132350 While the exact cellular function of bcl7a is unknown at present, its expression has been shown to be diminished in mycosis fungoides and ptcl compared with lymphoblastic lymphoma indicating possible contribution to lymphoid malignancies arising from mature t cells.
PubMedID- 21994857 Hepatocellular carcinoma (hcc) in one patient and hepatosplenic lymphoma, a rare type of peripheral t-cell lymphoma with rearrangement of the γδt-cell receptor, have been reported [30, 81, 82].
PubMedID- 22770229 Unlike other non-hodgkin's lymphomas, only two subtypes of peripheral t-cell lymphomas are characterized by disease-defining genetic abnormalities, such as the t(2;5)(p23;q35) in anaplastic large-cell lymphoma and dna integration of human t-lymphotropic virus 1 (htlv1) in adult t-cell leukemia/lymphoma [5,6].
PubMedID- 20141444 Like aggressive b-cell non-hodgkin lymphoma, the risk of developing ptcl is also increased in the setting of hiv infection.

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