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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease pancytopenia
Comorbidity C0040034|thrombocytopenia
Sentences 11
PubMedID- 24273485 Larger groups in need are patients with myelodysplastic syndrome, chemotherapy-induced thrombocytopenia, other forms of hereditary and acquired bone marrow failure, hepatitis c infections, or liver cirrhosis.
PubMedID- 23690288 Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of tpo receptor agonists in aplastic anemia and myelodysplastic syndromes.
PubMedID- 25995815 Hematologic manifestations of gd include pancytopenia with anemia, thrombocytopenia and less commonly leucopenia [14].
PubMedID- 21316823 Platelet transfusions are mainly used for patients with thrombocytopenia due to bone marrow failure, especially cancer patients developing severe chemotherapy-induced thrombocytopenia (e.g.
PubMedID- 21327404 Increased requirement for platelet transfusions concurrent with enhanced bleeding during romiplostim treatment in a patient with thrombocytopenia due to bone marrow failure.
PubMedID- 20678341 Laboratory tests showed pancytopenia with severe thrombocytopenia (thrombocyte count 4.0 × 109 cells/l, erythrocyte count 3.34 × 1012 cells/l, leukocyte count 2.92 × 109 cells/l).
PubMedID- 23788909 The most common undesirable effects of gemcitabine include pancytopenia, with thrombocytopenia associated with gemcitabine's myelosuppressive activity.
PubMedID- 20101676 pancytopenia with severe thrombocytopenia in a patient treated with twice-weekly ldl-apheresis by polyacrylate adsorption from whole blood.
PubMedID- 20237930 The present case suggests that pancytopenia with severe thrombocytopenia can be a difficult-to-treat abnormality, and initial manifestation of primary ss and ivig might be an effective treatment for severe thrombocytopenia refractory to high-dose steroid in primary ss.
PubMedID- 24778999 Organ infiltration by mc may lead not only to organomegaly, but also to impairment or even loss of organ function and in severe (high grade) disease, bone marrow failure with anemia, thrombocytopenia, and/or recurrent infections (due to neutropenia) may occur.
PubMedID- 23284257 (7,8) this is achieved in transfusion medicine using platelet concentrates (pcs), which allow the infusion of large quantities of platelets in small volumes of fluid; this is especially indicated for thrombocytopenia due to bone marrow failure.

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