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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease pancytopenia
Comorbidity C0001815|myelofibrosis
Sentences 2
PubMedID- 20441585 These mice also show bone marrow failure with myelofibrosis and higher frequencies of hematologic malignancies, providing evidence that arid4a functions as a tumor suppressor gene and its absence is permissive for the proliferation of connective tissue elements.
PubMedID- 24454890 88 developed myelofibrosis with pancytopenia 10 years after a diagnosis of “et” in 1990 (likely prefibrotic myelofibrosis); the patient died 18 years from diagnosis due to septicemia.

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