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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease osteochondroma
Comorbidity C0008479|chondrosarcoma
Sentences 4
PubMedID- 23576074 We report a case of a 34-year-old man with a chondrosarcoma arising from an osteochondroma of the left posterior eighth rib that developed following total body irradiation received as part of the conditioning regimen prior to bone marrow transplantation at age 8.
PubMedID- 22555180 However, despite the substantial agreement, we demonstrated that histology alone cannot distinguish osteochondroma from low-grade secondary peripheral chondrosarcoma in the setting of multiple osteochondromas, as nodularity, the presence of binucleated cells, irregular calcification, cystic/mucoid changes and necrosis were not helpful to indicate malignant transformation of an osteochondroma.
PubMedID- 26064741 Ct guided biopsy of the left abdominal mass confirmed the diagnosis of a low-grade chondrosarcoma arising from an osteochondroma from the lateral body of the l3 vertebrae.
PubMedID- 20467466 Histopathologic examination revealed a well-differentiated chondroid neoplasm composed of abundant hypercellular nodules of hyaline cartilage consistent with a low-grade chondrosarcoma arising from an osteochondroma (figure 6), similar to findings noted on biopsy.

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