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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease optic neuritis
Comorbidity C0011303|demyelinating disease
Sentences 5
PubMedID- 22831763 The 81% seropositivity rate in "unclassified" patients suggests that aqp4 autoimmunity accounts for a significant proportion of thai cns inflammatory demyelinating disease, especially those with optic neuritis or transverse myelitis, with or without abnormal brain mri, in whom a specific diagnosis or clear-cut treatment approach is unclear.
PubMedID- PMC2924520 Corticosteroid-sparing immunosupressive agents and intravenous immunoglobulins (ivig) have been reported to allow decrease in dose, and in some cases, discontinuation of oral steroids, in patients with corticosteroid-dependent autoimmune optic neuropathy and optic neuritis not associated with demyelinating disease.
PubMedID- 20436750 Have described corticosteroid dependent optic neuritis, not associated with demyelinating disease.
PubMedID- 20463974 Background: neuromyelitis optica (nmo), a severe demyelinating disease, represents itself with optic neuritis and longitudinally extensive transverse myelitis.
PubMedID- 26496907 Acquired pediatric demyelinating diseases manifest acutely with optic neuritis, transverse myelitis, acute disseminated encephalomyelitis, or with various other acute deficits in focal or polyfocal areas of the central nervous system.

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