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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease open-angle glaucoma
Comorbidity C0020538|hypertension
Sentences 13
PubMedID- 22833783 In humans, pigment dispersion syndrome only leads to pathological ocular hypertension (pigmentary glaucoma) and rgc loss in a subset of patients41.
PubMedID- 21035866 Purpose: to test the hypothesis that neodymium:yttrium-aluminum-garnet (nd:yag) laser peripheral iridotomy (lpi) significantly reduces the incidence of conversion from pigment dispersion syndrome (pds) with ocular hypertension (oht) to pigmentary glaucoma (pg).
PubMedID- 21670344 Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with hypertension, alcohol intake, and cigarette smoking.
PubMedID- 25813999 Purpose: the pathophysiology of ocular hypertension (oh) leading to primary open-angle glaucoma shares many features with a secondary form of oh caused by treatment with glucocorticoids, but also exhibits distinct differences.
PubMedID- 19850843 Methods: thirty subjects under treatment for open-angle glaucoma, 23 subjects with ocular hypertension, and 28 healthy subjects in a control group were investigated by monocular pattern electroretinogram (erg), l&m (long and medium wavelength) cone erg, and s (short wavelength)-cone erg.
PubMedID- 19432875 Purpose: to estimate the effect of reducing intraocular pressure (iop) on: (i) the incidence of primary open-angle glaucoma (poag) in patients with ocular hypertension (oh), and (ii) the progression of glaucoma.
PubMedID- 24879946 Purpose: to conduct a systematic review and meta-analysis of the association between blood pressure levels and hypertension with primary open-angle glaucoma and intraocular pressure endpoints.
PubMedID- 25370392 Aims: to study the relationship between blood pressure (bp), intraocular pressure (iop), mean ocular perfusion pressure (mopp) and primary open angle glaucoma (poag) in patients with hypertension and compare it to a control group of normotensives.
PubMedID- 25863852 Repeated intravitreal anti-vascular endothelial growth factor injections can induce iatrogenic ocular hypertension, especially in patients with open-angle glaucoma.
PubMedID- 24620786 Background: to evaluate the clinical utility of spectral analysis of intraocular pressure pulse wave in healthy eyes of a control group (cg), patients having glaucomatous optic disc appearance or ocular hypertension, and patients with primary open angle glaucoma or primary angle closure glaucoma.
PubMedID- 21705084 Purpose: to determine if the accuracy of the baseline prediction model for the development of primary open-angle glaucoma (poag) in patients with ocular hypertension can be improved by correcting intraocular pressure (iop) for central corneal thickness (cct).
PubMedID- 20582862 This conference report highlights selected presentations on the development of fov-2304 (fovea pharmaceuticals sa) for the potential treatment of diabetic macular edema; pha-666859 (pfizer inc) for diabetic retinopathy; gtx-878 (gtx inc) and fcfd-4514s (genentech inc) for age-related macular degeneration; syl-040012 (sylentis sau) for ocular hypertension associated with open-angle glaucoma; peg-pla-tnp-470 (harvard medical school) for ocular neovascularization; recombinant galectin-3 (senju pharmaceutical co ltd) for corneal injury; and cellbead neuro (cellmed inc) for neurological trauma and neurodegeneration.
PubMedID- 20181282 Reducing iop prevents or delays the onset of open-angle glaucoma in patients with ocular hypertension [3] and slows progression among those with open-angle glaucoma [4-8].

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