eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | noonan syndrome |
| Comorbidity | C0023418|leukaemia |
| Sentences | 1 |
| PubMedID- 24803665 | For example, tartaglia and colleagues assessed ptpn11 (shp2) mutations by comparing somatic mutations in juvenile myelomonocytic leukaemia (jmml) with noonan syndrome germline mutations, and they identified a greater activation of the ras/mapk activation for the jmml‐associated mutations (tartaglia et al, 2003). |
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