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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease non-alcoholic fatty liver disease
Comorbidity C0023890|cirrhosis
Sentences 21
PubMedID- 20030578 The aims of this study were (1) to evaluate the presence of nafld in patients with cryptogenic cirrhosis evaluated for olt and (2) to compare the severity of liver disease and patient survival in olt candidates with cryptogenic cirrhosis and those with cirrhosis of another known origin.
PubMedID- 23000435 We report the case and discuss the outcome of a 63-year-old man, who was transplanted for hepatocellular carcinoma arising from cirrhosis associated with non-alcoholic fatty liver and diabetes.
PubMedID- 26473344 nonalcoholic fatty liver disease (nafld) can lead to cirrhosis, hepatocellular carcinoma, and ultimately death.
PubMedID- 24251711 In our second analysis, the hcc development rates among liver cirrhosis with nafld, alcoholic cirrhosis, and cirrhosis with hepatitis c virus (hcv) were compared.
PubMedID- 25678995 We aimed to design an artificial neural network (ann) model to diagnose cirrhosis patients with non-alcoholic fatty liver disease (nafld) using routine laboratory data.
PubMedID- 25175670 Case presentation: a 76-year-old caucasian man with liver cirrhosis due to non-alcoholic fatty liver disease, and type-2 diabetes was cognitively impaired and had reduced vigilance presumably caused by hepatic encephalopathy and/or alzheimer dementia.
PubMedID- 25971926 Background: maternal obesity increases offspring propensity to metabolic dysfunctions and to non-alcoholic fatty liver disease (nafld), which may lead to cirrhosis or liver cancer.
PubMedID- 20101745 The aim of this study was to evaluate the accuracy of transient elastography for the diagnosis of fibrosis and cirrhosis in patients with nafld and to study factors associated with discordance between transient elastography and histology.
PubMedID- 22576780 Background: non-alcoholic fatty liver disease (nafld) can lead to cirrhosis and hepatocellular carcinoma and is strongly associated with obesity and insulin resistance.
PubMedID- 21512848 All deaths in the nafld group were in patients with nash-related cirrhosis who had undergone right hemihepatectomy.
PubMedID- 21991518 A number of risk factors have been identified as predictors for progressive fibrosis and cirrhosis in nafld including; bmi > 30, type ii diabetes, age > 45 years, and an alt : ast ratio > 1 [7].
PubMedID- 24129500 Purposes: hepatic lipid overloading induces lipotoxicity which can cause hepatocyte damage, fibrosis, and eventually progress to cirrhosis, which is associated with nonalcoholic fatty liver disease.
PubMedID- 23760378 Of the 203 patients with cryptogenic chronic liver disease, 39 had liver biopsy - amongst the latter, idiopathic non cirrhotic intrahepatic portal hypertension (nciph) was seen in 16 patients (41%), while five patients had cirrhosis due to non alcoholic fatty liver disease.
PubMedID- 23420151 Obesity and diabetes are predictors of advanced liver fibrosis and cirrhosis in nafld patients (2).
PubMedID- 22813407 Background: nonalcoholic fatty liver disease (nafld), a common cause of cryptogenic cirrhosis is often associated with metabolic syndrome (ms) in the west.
PubMedID- 26189985 When unchecked, both nafld and afld lead to steatohepatitis, fibrosis, cirrhosis, hepatocellular carcinoma (hcc) and eventual death.
PubMedID- 22418891 Immunostains for cytokeratin 7, ubiquitin, and glutamine synthetase provided additional histologic data supporting nafld as the cause of the cirrhosis in this case.
PubMedID- 23886860 Mice fed a diet containing 40% fat (of which approximately 18% was trans fat), 22% fructose, and 2% cholesterol developed three stages of nonalcoholic fatty liver disease (steatosis, steatohepatitis with fibrosis, and cirrhosis) as assessed by histological and biochemical methods.
PubMedID- 23859493 Conclusion: te plays an important role in the detection of advanced fibrosis and cirrhosis in patients with nafld and its accuracy does not appear to be influenced by components of the disease.
PubMedID- 22655206 It is part of the spectrum of nonalcoholic fatty liver disease (nafld) that can lead to cirrhosis in patients without a history of alcohol abuse and whose prevalence is increasing in western countries because of the obesity and diabetes mellitus incidence.
PubMedID- 22102439 Although other outcomes related to non-alcoholic fatty liver disease, including cirrhosis, cancer, and a more rapid progression of coexistent liver diseases may be important, our findings support the suggestion that people with accumulation of fat in the liver have a good prognosis with respect to mortality.

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