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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease non-alcoholic fatty liver disease
Comorbidity C0004153|atherosclerosis
Sentences 26
PubMedID- 21664615 We evaluated liver mrna expression of 84 genes encoding proteins involved in the atherosclerosis pathway in patients with nafld proven through biopsy in a case-control design, and examined the putative role of the histological disease severity in the molecular events associated with the atherogenic profile.
PubMedID- 24069270 Pnpla3 gg genotype and carotid atherosclerosis in patients with non-alcoholic fatty liver disease.
PubMedID- 22814750 nonalcoholic fatty liver disease is associated with atherosclerosis in middle-aged and elderly chinese.
PubMedID- 23626730 Background: non-alcoholic fatty liver disease (nafld) is associated with cardiovascular atherosclerosis independent of classical risk factors.
PubMedID- 23834053 nafld correlates with atherosclerosis, insulin resistance and diabetes mellitus.
PubMedID- 21525484 Several alterations that are linked with the pathogenesis of atherosclerosis were reported in patients with nafld, including endothelial dysfunction, alterations of the coronary and carotid arteries, abnormal cardiac energy metabolism, and low-grade inflammation.
PubMedID- 22676459 Background: insulin resistance (ir) is the major driving force behind development and progression of atherosclerosis in patients with nonalcoholic fatty liver disease (nafld).
PubMedID- 21504583 nafld is associated with accelerated atherosclerosis [10], and oxidative stress is now believed to be an important factor in the development/progression of the condition [3-5].
PubMedID- 23085576 Evaluation of early atherosclerosis markers in patients with nonalcoholic fatty liver disease.
PubMedID- 22385985 Objectives: hcv and nafld are associated with atherosclerosis in general population.
PubMedID- 25729707 A recent comprehensive systematic review of 27 studies showed that nafld is associated with subclinical atherosclerosis independent of traditional risk factors and metabolic syndrome and across a wide range of ethnicities [4].
PubMedID- 22359630 Objectives: nonalcoholic fatty liver disease (nafld) is associated with advanced atherosclerosis and a higher risk of cardiovascular disease.
PubMedID- 25436098 (2007) showed increased liver enzymes in patients with nafld might be associated with severity of atherosclerosis (19).
PubMedID- 20835270 Clinical studies showed that the severity of histopathological features in nafld is strongly associated with early carotid atherosclerosis, insulin resistance, and the presence of metabolic syndrome34.
PubMedID- 25500875 For instance, our previous study found that nafld was associated with atherosclerosis in middle-aged and elderly chinese individuals, independent of conventional cardiovascular disease risk factors or metabolic syndrome5.
PubMedID- 24956534 In a population-based cross-sectional sample of middle-aged adults free from liver or heart disease, we tested the hypothesis that nafld is associated with subclinical atherosclerosis (coronary artery (cac) and abdominal aortic calcification (aac)) independent of obesity.
PubMedID- 23185655 Conclusion: nafld is significantly associated with carotid atherosclerosis in non-diabetic outpatients even without mets.
PubMedID- 22748277 nonalcoholic fatty liver disease is associated with subclinical atherosclerosis independent of obesity and metabolic syndrome in asian indians.
PubMedID- 24794207 Adiponectin has recently been considered as a possible link between liver dysfunction and atherosclerosis in patients with nonalcoholic fatty liver disease (nafld).
PubMedID- 25300437 We examined whether transient elastography (te) defined nafld was associated with atherosclerosis in rtrs, as measured by ultrasound in the carotid arteries.
PubMedID- 24381427 A study of carotid atherosclerosis in patients with non-alcoholic fatty liver disease.
PubMedID- 24075754 Conclusion: there is evidence to support the association of nafld with subclinical atherosclerosis independent of traditional risk factors and metabolic syndrome.
PubMedID- 25816034 In contrast to our findings, vanwagner et al34 demonstrated that nafld was not associated with subclinical atherosclerosis as measured by coronary artery calcification, and tarantino et al35 also indicated that the severity of hepatic steatosis was not associated with carotid intima media thickness in obese patients.
PubMedID- 23924883 Conclusions: patients with smaller retinal avr (<0.7) are likely to be at increased risk for cad and carotid atherosclerosis in patients with nafld even without hypertension or diabetes.
PubMedID- 24328674 Endothelial dysfunction and carotid atherosclerosis in non-alcoholic fatty liver disease.
PubMedID- 25603326 Association of nafld with subclinical atherosclerosis and coronary-artery disease: meta-analysis.

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