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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease neutropenia
Comorbidity C1140680|ovarian cancer
Sentences 2
PubMedID- 24657302 Objective: evaluate the cost-effectiveness of primary prophylaxis (pp) or secondary prophylaxis (sp) with pegfilgrastim, filgrastim (6-day and 11-day), or no prophylaxis to reduce the risk of febrile neutropenia (fn) in patients with recurrent ovarian cancer receiving docetaxel or topotecan.
PubMedID- 24761216 Clinical trials have reported that the incidence of febrile neutropenia in patients with ovarian cancer receiving paclitaxel and carboplatin (tc) chemotherapy is<10% [9,10], and the guidelines indicate that csfs are not needed for primary prophylaxis in these patients.

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