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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease neutropenia
Comorbidity C0020532|hypersplenism
Sentences 7
PubMedID- 24872634 If a considerable proportion of hemolysis takes place in the spleen, as is often the case, splenomegaly may become a prominent feature and hypersplenism may develop, with consequent neutropenia and/or thrombocytopenia resulting in pancytopenia.
PubMedID- 23420139 While in some patients the disease remained static, in a larger proportion a more severe disease developed characterized by portal hypertension, the latter leading to hypersplenism with neutropenia and thrombocytopenia and, in some cases, to ascites.
PubMedID- 21734807 Aim: to study the safety and feasibility of total embolization of the main splenic artery as a supplemental treatment modality for hypersplenism with thrombocytopenia or leukocytopenia accompanying liver cirrhosis.
PubMedID- 24255616 Lower values ofplatelet counts are seen especially in patients with hs after gastrointestinal bleeding.this was also seen in the current work with the possible cause being the increase ofspleen and hypersplenism leading to frequent thrombocytopenia, leukopenia and anemia.
PubMedID- 23132324 The indications for surgery were pain and discomfort caused by a large spleen (5-15 cm below the costal margin) and symptomatic hypersplenism with leucopenia, thrombocytopenia, and anemia.
PubMedID- 22043264 hypersplenism can lead to anemia, leukopenia, and thrombocytopenia.
PubMedID- 25233685 Indications for surgery were pain and abdominal discomfort caused by spleen enlargement, as well as symptomatic hypersplenism with leucopenia, thrombocytopenia and anemia.

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