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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease neutropenia
Comorbidity C0011991|diarrhoea
Sentences 3
PubMedID- 20628391 In a multivariate logistic regression analysis, ugt1a1*28/*28 genotype was an independent predictive factor of haematologic toxicity and severe neutropenia with or without diarrhoea at the end of treatment.
PubMedID- 23666916 Fluorouracil dose was reduced to 2400 mg/m(2) after two of the first three patients reported grade 3-4 diarrhoea (in one case with febrile neutropenia).
PubMedID- 22997602 The most common toxicity was diarrhoea in two thirds of patients and neutropenia in 60% [54].

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