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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease neutropenia
Comorbidity C0002871|anemia
Sentences 21
PubMedID- 25006294 There was anemia (hemoglobin of 9.7 g/dl) and leucopenia (white blood cells count 2800/mm3) but the absolute neutrophil count (1700/mm3) and platelets were normal.
PubMedID- 24833969 Other abnormal findings were thrombocytopenia, anemia, and leukopenia withmarked neutropenia but with normal lymphocytic and monocytic series.
PubMedID- 24198852 This includes hemolytic anemia with reticulocytosis, leucopenia (<4.0x10⁹/l) or lymphopenia (<1.5x10⁹/l) on two or more occasions, or thrombocytopenia (<100x10⁹/l) in the absence of offending drugs [4,5].
PubMedID- 24864270 This ongoing registry had recruited 2170 chinese sle patients who fulfilled the sle classification criteria revised by the american college of rheumatology (acr) in 1997 [9] during the period between april 2009 and february 2010. patients were required to fulfill at least 4 of the following 11 criteria: (1) malar rash; (2) discoid rash; (3) photosensitivity; (4) oral or nasopharyngeal ulceration; (5) nonerosive arthritis involving 2 or more peripheral joints; (6) pleuritis or pericarditis; (7) nephropathy: persistent proteinuria > 0.5 grams per day or cellular casts; (8) neurologic involvement: seizures or psychosis in the absence of offending drugs or known metabolic derangements; (9) hematologic involvement: hemolytic anemia with reticulocytosis or leukopenia (<4,000/mm3 on ≥2 occasions) or lymphopenia (<1,500/mm3 on ≥2 occasions) or thrombocytopenia (<100,000/mm3) in the absence of offending drugs; (10) immunologic disorder: antibody to native double-stranded dna in abnormal titer or presence of antibody to sm nuclear antigen or positive finding of antiphospholipid antibodies; (11) positive antinuclear antibody.
PubMedID- 23064040 The results showed that in 35 sle patients, 20 patients had leukopenia, 24 with anemia or thrombocytopenia.
PubMedID- 21306603 Records of clinical and laboratory findings during the study period were collected as follows: hemolytic anemia with reticulocytosis, leucocytopenia (< 4000 cells/mm3) and lymphopenia [absolute lymphocytic count (alc) <1,500 cells/mm3 ] present in 2 or more occasions, thrombocytopenia (< 100,000 cells/mm3) in the absence of offending drugs, abnormal urinalysis (proteinuria 0.5 g/24 h or >3+ if quantitative evaluation was not done, and/or casts, hematuria >5 rbcs/hpf or pyuria >5 wbcs/hpf in the absence of infection), increased creatinine (> 1 mg/dl), low c3, increased erythrocyte sedimentation rate (esr) (> 20 mm/hr).
PubMedID- 24555093 Laboratory tests upon admission showed severe neutropenia with moderate anemia and thrombocytopenia, increased prothrombin time (pt), partial thromboplastin time (ptt) and low fibrinogen (table 2).
PubMedID- 21597288 Grade 3 and 4 toxicities included anemia (20.5% of patients), thrombocytopenia (2.3%), neutropenia (10.3%), aspartate transaminase increase (10.3%), alanine transaminase increase (5.1%) and emesis (5.1%).
PubMedID- 25853131 Cytopenia include anemia (adeficiency of rbcs), leukopenia or neutropenia (a deficiency of wbcs or leukocytes), thrombocytopenia (a deficiency of platelets), and pancytopenia (a deficiency of all three blood cell types—rbc, wbc, and platelet) (smith, 2010).
PubMedID- 21989989 Rps19-deficient mice develop a macrocytic anemia together with leukocytopenia and variable platelet count that with time leads to the exhaustion of hematopoietic stem cells and bone marrow failure.
PubMedID- 23056691 In our patient the main manifestations were neurological features (seizures, developmental regression, brain atrophy), and hematologic (macrocytic sideroblastic anemia, vacuolization of hematopoietic precursors and neutropenia).
PubMedID- 21367725 Background: persistent neutropenia associated with severe aplastic anemia (saa) is an important risk factor for development of life-threatening infections.
PubMedID- 24505539 Regarding, chemotherapy-related complications in the first group, two patients had anemia, two of them had neutropenia, one had thrombocytopenia, and another one skin lesions.
PubMedID- 22235047 Laboratory tests showed anemia with leucopenia, hypocomplementemia, proteinuria, ana positive at 1:320, and antibodies against dsdna, ro/ssa, la/ssb and histone.
PubMedID- 21772952 Evans syndrome (es) is an autoimmune disorder characterized by thrombocytopenia and/or neutropenia associated with hemolytic anemia (aha).1–3 it is a potentially life-threatening condition that may be associated with other underlying autoimmune or lymph-proliferative disorders.4 standard treatment consists of transfusions, corticosteroids and immunoglobulins (ivig); second-line treatment in es evolved over the last decade, and includes at present anti-cd20 rituximab, vincristine, alkalizing agents, mycophenolate mofetil (mmf) or cyclosporine (cya).5–6,8–14 long-term remissions induced by splenectomy are less frequent than in uncomplicated immune thrombocytopenia purpura (itp).
PubMedID- 21998605 Peripheral blood smear showed normochromic normocytic anemia with anisopoikilocytosis 2+, neutropenia, lymphocytopenia, relative monocytosis 14%, and thrombocytopenia.
PubMedID- 26063969 Hemolytic anemia with reticulocytosis or leukopenia <4.000/mm3 on ≥2 occasions or lymphopenia <1.500/mm3 on ≥2 occasions or thrombocytopenia <100.000/mm3 in the absence of offending drugs.
PubMedID- 22368952 Hemograms showed anemia in 95% of cases, leucopenia in 20%, neutropenia in 35%, lymphopenia in 42%, and thrombopenia in 3%.
PubMedID- 25867940 Hematologic abnormalities included moderate nonregenerative anemia, leucopenia with neutropenia, and moderate thrombocytopenia.
PubMedID- 25656675 anemia occurs in 20% of patients and leucopenia is less common (1, 5).
PubMedID- 24368919 Normocytic anemia with hemoglobin level of 11.3 g/dl without leukopenia or thrombocytopenia was shown.

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