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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease neuropathy, peripheral
Comorbidity C0035309|retinopathy
Sentences 5
PubMedID- 21273496 In multivariate analyses (or; 95% ci), male sex (3.90; 2.29–6.65), heavy smoking (2.07; 1.11–3.85), hypertension (3.36; 1.91–5.93), diabetic retinopathy (2.62; 1.13–6.09), history of peripheral neuropathy (1.68; 1.02–2.76), and higher hba1c level (per 1% 1.40; 1.24–1.58) were independently associated with 25-year incidence of lea.
PubMedID- 22988507 Furthermore, t2dm is most common in older adults, who as a result of this disease often experience various comorbidities [49], further reducing their capacity to live independently (e.g., retinopathy, which may lead to blindness; peripheral neuropathy, which may lead to foot ulcers and amputations; nephropathy, which over time could result in renal failure, etc.).
PubMedID- 21523218 The chronic hyperglycemia associated with diabetes leads to long-term complications including cvd, nephropathy leading to renal failure, retinopathy with potential loss of vision, and peripheral neuropathy (27).
PubMedID- 26520862 retinopathy was assessed with retinal images, peripheral neuropathy was assessed clinically with monofilament and biothesometer in selected patients.
PubMedID- 25699225 Nephropathy leading to renal failure; retinopathy with loss of vision; peripheral neuropathy with risk of foot ulcers and amputations are long-term complications of diabetes [1].

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