eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | neuropathy, peripheral |
| Comorbidity | C0026764|multiple myeloma |
| Sentences | 12 |
| PubMedID- 20932799 | Treatment-related peripheral neuropathy in multiple myeloma: the challenge continues. |
| PubMedID- 21654882 | Its marked safety and comparable efficacy in multiple myeloma patients with pre-existing peripheral neuropathy makes it a drug that will integrate well with other active agents. |
| PubMedID- 22110934 | peripheral neuropathy in patients with multiple myeloma occurs as both disease- and treatment-related complication in the relapsed and newly diagnosed setting. |
| PubMedID- 24505516 | The condition may occur before initiating treatment.32 in a recent study by borrello et al., the incidence of peripheral neuropathy in patients with newly diagnosed multiple myeloma prior to the administration of any therapy was 15% which suggests that peripheral neuropathy is a symptom of the disease itself.33 furthermore, treating multiple myeloma might complicate the neuropathy; the latter is associated with agents used to treat the disease, such as bortezomib,7 thalidomide,34 and vincristine.35 recently, wilson and vallance-owen have suggested an interaction between myeloma-related factors and the patient's genetic background in the development of treatment-induced peripheral neuropathy with different molecular pathways being implicated in bortezomib-induced and vincristine-induced peripheral neuropathy.29 patients frequently complain of sensory symptoms, pain in a stocking-and-glove distribution, and proprioception changes that may affect normal daily living activities.36 studies looking into the association between bortezomib-induced neuropathy and diabetic neuropathy have yielded contradictory results. |
| PubMedID- 21749306 | Prevalence of peripheral neuropathy in multiple myeloma at initial diagnosis. |
| PubMedID- 22297012 | Bortezomib-induced peripheral neuropathy in patients with multiple myeloma. |
| PubMedID- 22363889 | In a recent study by borrello et al., the incidence of peripheral neuropathy in patients with newly diagnosed multiple myeloma prior to the administration of any therapy was 15% which suggests that peripheral neuropathy is a symptom of the disease itself [33]. |
| PubMedID- 20467223 | [severe bortezomib-induced peripheral neuropathy in a patient with multiple myeloma]. |
| PubMedID- 24867959 | A pilot study of acupuncture in treating bortezomib-induced peripheral neuropathy in patients with multiple myeloma. |
| PubMedID- 25154818 | Subclinical peripheral neuropathy in patients with multiple myeloma before chemotherapy is correlated with decreased fingertip innervation density. |
| PubMedID- 22193964 | Management of treatment-emergent peripheral neuropathy in multiple myeloma. |
| PubMedID- 23372151 | peripheral neuropathy in multiple myeloma patients receiving lenalidomide, bortezomib, and dexamethasone (rvd) therapy. |
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