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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease neuroepithelioma
Comorbidity C0494165|liver metastases
Sentences 10
PubMedID- 26111625 Purpose: studies have reported limited evidence of the benefits and harms of various regimens, such as liver resection and medical therapy, for the treatment of pancreatic neuroendocrine tumors (pnets) with liver metastases.
PubMedID- 21816425 Methods: primary tumors (n = 38) and corresponding lymph node (n = 5) and liver metastases (n = 9) of patients with pnet, treated at the university medical center hamburg-eppendorf between 1993 and 2006, were analyzed via alcam immunohistochemistry in a tissue microarray format.
PubMedID- 25822862 Objective: to investigate the usefulness of serum chromogranin a (cga) for the prediction of tumor burden, therapeutic response, and nomogram-based survival in well-moderate nonfunctional pancreatic neuroendocrine tumors (nf-pnets) with liver metastases (lms).
PubMedID- 25780425 The final diagnosis was intestinal pnet with liver metastases.
PubMedID- 23846939 In the management of patients of pnets with unresectable liver metastases, the clinical efficacy of surgery to primary pancreatic tumor has been controversial.
PubMedID- 24658317 Our similar results show that liver-directed strategies for pnets with liver metastases seem to be associated with a prolonged os and metastatic relapse time and patients with nonfunctional hepatic metastasis derive the greatest survival benefit.
PubMedID- 26043944 Background: the value of surgical resection in the management of pancreatic neuroendocrine tumors (pnet) with liver metastases (lm) is still debated.
PubMedID- 25692122 In conclusion, if there is no other distant metastasis, for pnets with unresectable synchronous liver metastases, a multidisciplinary approach could be helpful with transarterial treatment and other systemic treatment.
PubMedID- 25241033 Small bowel (sbnets) and pancreatic neuroendocrine tumors (pnets) often present with liver metastases.
PubMedID- 21358176 Methods: medline was queried for studies reporting the outcome of pnet patients with unresectable liver metastases whenever there was an explicit comparison between resection of the primary lesion only ('active treatment') and no resection ('non-active treatment').

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