eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | nephrotic syndrome |
| Comorbidity | C0398623|hypercoagulable state |
| Sentences | 5 |
| PubMedID- 21886984 | [7] steroids shorten prothrombin as well as accelerate partial thromboplastin times that aggravate the hypercoagulable state of nephrotic syndrome. |
| PubMedID- 21917124 | hypercoagulable state associated with nephrotic syndrome and antiphospholipid syndrome can lead to the development of occlusive coronary artery thrombus in absence of atherosclerotic coronary artery disease. |
| PubMedID- 25984105 | In fact, despite the underlying causes of the hypercoagulable state in patients with nephrotic syndrome that are not well understood, a variety of haemostatic abnormalities have been described, including decreased levels of antithrombin and plasminogen (due to urinary losses), increased platelet activation, hyperfibrinogenaemia, inhibition of plasminogen activation, and the presence of high-molecular-weight fibrinogen moieties in the circulation [11]. |
| PubMedID- 23580806 | [10] described two adult patients, 34 and 36 years of age, who presented with acute cerebral infarction and were found to have a hypercoagulable state due to nephrotic syndrome. |
| PubMedID- 25607275 | nephrotic syndrome is associated with a hypercoagulable state and an increased risk of thromboembolic complications. |
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