eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | nasopharyngeal carcinoma |
| Comorbidity | C0205698|undifferentiated carcinoma |
| Sentences | 3 |
| PubMedID- 21658269 | The undifferentiated carcinoma of the nasopharynx is a common cancer in north africa and in the mediterranean basin, but the incidence of a double malignancy including a nasopharyngeal carcinoma is very uncommon. |
| PubMedID- 23816561 | The eligibility criteria included biopsy-diagnosed non-keratinizing or undifferentiated carcinoma of the nasopharynx, as defined by the who classification[14]; stage iii or iva and ivb disease, as defined by the international union against cancer staging system (2002 uicc 6th edition), with no gross evidence of distant metastasis[15]; 18 to 60 years old; adequate hematologic function with a total leukocyte count (wbc)≥4,000 cells/ml and platelet count≥100,000 platelets/ml; adequate hepatic and renal functions with normal serum bilirubin, alanine aminotransferase (alt), and alkaline phosphatase (alp) levels of less than two times the upper limit of normal, and a 24-hour creatinine clearance (crcl)≥=60 ml/min; and satisfactory performance status (≤2) as defined by the eastern cooperative oncology group system[16]. |
| PubMedID- 20592893 | In italian patients with undifferentiated carcinoma of the nasopharynx, it has been reported that il-10 -1082a>g, -819c>t, and -592a>c snps were not associated with cancer development (26). |
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