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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease myelofibrosis
Comorbidity C0001815|myeloid metaplasia
Sentences 9
PubMedID- 22548075 Most of the reported pulmonary extramedullary hematopoiesis is seen in myelofibrosis with myeloid metaplasia, a subgroup of chronic myeloproliferative disorders.
PubMedID- 19785025 Chronic idiopathic myelofibrosis (cim) with myeloid metaplasia is a myeloproliferative disorder characterized by leukoerythroblastosis, tear drop erythrocytes, extra-medullary hematopoesis (emh), and varying degree of myelofibrosis.
PubMedID- 23259545 myelofibrosis with myeloid metaplasia (mmm) is a rare malignant hematological disease of the hematopoietic stem cells with a median age at diagnosis of 60 years.
PubMedID- 21224796 Aim: in this paper we retrospectively analyzed prospectively-collected data on our myelofibrosis with myeloid metaplasia (mmm) patients who underwent splenectomy.
PubMedID- 22282696 Increase in fibrosis is due to liberation of cytokines such as tgf-β and pdgf from dysplastic megakaryocytes.15 the differential diagnosis includes myelofibrosis with myeloid metaplasia, chronic myelocytic leukemia and acute megakaryocytic leukemia.
PubMedID- 21870730 [myeloid metaplasia with myelofibrosis associated with acute coronary syndrome.
PubMedID- 20615740 Objective: lenalidomide (ldm) is an immunomodulatory and anti-angiogenic drug which has been shown to be effective in several haematological disorders (multiple myeloma [mm], myeloid metaplasia with myelofibrosis [mf] and myelodysplastic syndrome [mds]).
PubMedID- 24880208 Essential thrombocytosis (et) falls under the umbrella of myeloproliferative disorders, which also includes chronic myelogenous leukemia, polycythemia vera, and myelofibrosis with myeloid metaplasia.
PubMedID- 20359349 Clonal dysregulation linked to myeloproliferative neoplasms (mpn) arising from acquired mutations in the haematopoietic progenitor cells lead to a wide range of clonal haematological malignant diseases including polycythemia vera (pv), essential thrombocythemia (et), myeloid metaplasia with myelofibrosis (mmm), chronic myelomonocytic leukemia (cmml), chronic myelogenous leukemia (cml), hypereosinophilic syndrome (hes), and systemic mast cell disease (smcd)[1].

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