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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease muscular atrophy
Comorbidity C0600260|obstructive pulmonary disease
Sentences 5
PubMedID- 24915195 Background: skeletal muscle wasting commonly occurs in patients with chronic obstructive pulmonary disease (copd) and has been associated with the presence of systemic inflammation and endocrinological disturbance.
PubMedID- 22781565 Objective: to conduct a preliminary proteomic study of chronic obstructive pulmonary disease (copd) with peripheral skeletal muscle atrophy.
PubMedID- 24666540 Background: impaired skeletal muscle regeneration could contribute to the progression of muscle atrophy in patients with chronic obstructive pulmonary disease (copd).
PubMedID- 24228729 Rationale: locomotor muscle atrophy develops in patients with chronic obstructive pulmonary disease (copd) partly because of increased protein degradation by the ubiquitin-proteasome system.
PubMedID- 19520920 Skeletal muscle atrophy in individuals with advanced chronic obstructive pulmonary disease (copd) is associated with diminished quality of life, increased health resource use, and worsened survival.

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