eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | muscular atrophy |
| Comorbidity | C0011847|diabetes |
| Sentences | 5 |
| PubMedID- 25522723 | Type 1 diabetes is associated with skeletal muscle atrophy. |
| PubMedID- 25998196 | Skeletal muscle atrophy develops in patients with diabetes mellitus (dm), especially in type 1 dm, which is associated with chronic inflammation. |
| PubMedID- 20676329 | diabetes mellitus is associated with severe muscle wasting, and the risk of insulin resistance increases with aging, fat mass, and physical inactivity (24). |
| PubMedID- 21826997 | Conclusion: our results indicated that diabetes modulated the expression of murf1 leading to muscle wasting, and the mechanism might be involved with oxidative stress. |
| PubMedID- 22596176 | Type 2 diabetes has been associated with muscle atrophy and weakness in different clinical (26) and population-based samples (10), and diabetic neuropathy involving motor neurons has been suggested to be an important determinant of accelerated muscle atrophy and loss of muscle strength in patients with diabetes. |
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