eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | mucopolysaccharidosis is |
| Comorbidity | C0018801|heart failure |
| Sentences | 1 |
| PubMedID- 20360066 | It is known that timp-1 does more than inhibit mmps in patients with chronic heart failure.23 in chronic inflammatory states, timp-1 levels increase much more than do mmp levels, promoting collagen formation24 and myocardial fibrosis.25,26 our observations suggest that patients with higher timp-1 levels have more myocardial fibrosis, which could negatively affect the response to crt. |
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