eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | monoclonal gammopathy of uncertain significance |
| Comorbidity | C0026470|monoclonal gammopathy of uncertain significance |
| Sentences | 8 |
| PubMedID- 23125471 | Serum and urine protein electrophoresis studies were consistent with monoclonal gammopathy of uncertain significance (mgus), and bone marrow biopsy, fow cytometry and chromosome analysis excluded the presence of myelomatous disease. |
| PubMedID- 22983434 | It is now widely accepted that most, if not all, mm is preceded by a premalignant disease known as monoclonal gammopathy of uncertain significance (mgus).19 mgus is characterised by the abnormal proliferation of plasma cells in the bone marrow, while the patients remain asymptomatic.20 the signals that lead to the initiation of excessive plasma cell proliferation are, therefore, present within the bone marrow microenvironment before the onset of overt mm. |
| PubMedID- 24467750 | Interestingly, some months before this hospital admission, our patient was diagnosed with monoclonal gammopathy of uncertain significance, a well-known potential precursor of b-cell lymphoproliferative disorders [11]. |
| PubMedID- 24741263 | monoclonal gammopathy of uncertain significance (mgus) is the condition in which an underlying causative disease is not evident. |
| PubMedID- 21430775 | However, these abnormalities are likely insufficient for malignant transformation because they are also observed in the pre-malignant syndrome known as monoclonal gammopathy of uncertain significance (mgus). |
| PubMedID- 24517398 | For example, some patients with monoclonal gammopathy of uncertain significance (mgus), a condition characterized by the presence of a monoclonal immunoglobulin protein present in the serum, can progress to multiple myeloma [9]. |
| PubMedID- 24198839 | Other associated conditions included hiv infection [9, 11, 16, 20], ethanol abuse [1, 5], gastric carcinoma [14, 19], barrett esophagus [22], monoclonal gammopathy of uncertain significance [8], and concurrent hepatitis c infection and insulin-dependent diabetes mellitus [17]. |
| PubMedID- 24098716 | Exclusion criteria included the following: any previously known neuromuscular disease or condition at risk for peripheral neuropathy, such as diabetes, systemic diseases with renal, hepatic or thyroid dysfunction, alcohol abuse, hiv or hepatitis c infection, hematological diseases or monoclonal gammopathy of uncertain significance, vitamin b12 deficiency, connective tissue diseases (e.g. |
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