eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | metabolic syndrome x |
| Comorbidity | C0020619|hypogonadism |
| Sentences | 5 |
| PubMedID- 22313648 | Male partial hypogonadotrophic hypogonadism with gynaecomastia and metabolic syndrome. |
| PubMedID- 20835560 | Caldas et al.11 described the relationship between insulin and hypogonadism in men with metabolic syndrome and concluded that hypogonadism was associated with insulin resistance and may be a marker of metabolic abnormalities. |
| PubMedID- 22469460 | The significant inverse association between il-6 and t suggests an important role of low-grade visceral fat inflammation in the central hypogonadism associated with the metabolic syndrome. |
| PubMedID- 22031847 | Furthermore, the beneficial effects of gtx-024 on insulin sensitivity and triglycerides, known associations of hypogonadism with metabolic syndrome and cardiovascular risk [33–35], as well as the low cardiovascular risk observed in randomized clinical trials of testosterone supplementation [18], suggest that the overall cardiovascular risk/benefit ratio for gtx-024 is low. |
| PubMedID- 20938417 | Aim: the metabolic syndrome is associated with male hypogonadism, but specific studies about the mechanisms and treatment of the testosterone deficit are scanty. |
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