eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | metabolic syndrome x |
| Comorbidity | C0020538|hypertension |
| Sentences | 114 |
| PubMedID- 22261288 | Although more studies are needed to determine whether these short-term increases or the longer-term decreases in adiposity modify the risk on chronic diseases such as diabetes mellitus, hypertension or other components of the metabolic syndrome, the widely held concern that preterm babies have greater adiposity than their term peers, and that this is worsened by greater amounts of catch-up growth, are not supported by the available evidence. |
| PubMedID- 20813031 | The economic burden to the health service of metabolic syndrome in patients with hypertension was been estimated at €24,427, €1,900 and €4,877 million in germany, spain and italy and forecast to rise by 59%, 179% and 157% respectively by 2020. |
| PubMedID- 22473401 | metabolic syndrome was significantly associated with hypertension, insulin resistance, increased abdominal fat, and overweight. |
| PubMedID- 26447765 | hypertension, one diagnostic criterion of metabolic syndrome, is regulated by the renin-angiotensin system [8] and angiotensin ii (angii) is important as a target of antihypertensive drugs. |
| PubMedID- 24466463 | hypertension is a component of metabolic syndrome, and interestingly, certain aldh2 genotypes have also been proposed as risk factors for metabolic syndrome with liver dysfunction [5]. |
| PubMedID- 21286276 | Taken together, these data indicate that abnormalities of renal na+ handling play an important role in the development of hypertension associated with the metabolic syndrome. |
| PubMedID- 24843633 | Diabetic patients are often obese, which is frequently complicated by metabolic syndrome with hypertension or dyslipidemia26. |
| PubMedID- 23974905 | Our results provide novel insight into the potential clinical value of rd in the treatment of hypertension with metabolic syndrome. |
| PubMedID- 25659889 | Peripheral insulin resistance is a key component of metabolic syndrome associated with obesity, dyslipidemia, hypertension, and type 2 diabetes. |
| PubMedID- 23808212 | The article is concerned with modern methods of assessment of arterial hypertension in patients with metabolic syndrome and characteristics of modern antihypertensive drugs and its combinations necessary for the elderly. |
| PubMedID- 19626043 | This study was designed to separate minerals and fiber from other components of dash on blood pressure in abdominally obese metabolic syndrome subjects with prehypertension to stage 1 hypertension (obese hypertensives). |
| PubMedID- 20405160 | Modelling the costs of care of hypertension in patients with metabolic syndrome and its consequences, in germany, spain and italy. |
| PubMedID- 20176994 | Obese persons with metabolic syndrome often have associated with salt-sensitive hypertension, microalbuminuria, and cardiac dysfunction, and the plasma aldosterone level in one-third of metabolic syndrome patients is clearly elevated. |
| PubMedID- 23205504 | Exercise-induced hypertension in men with metabolic syndrome: anthropometric, metabolic, and hemodynamic features. |
| PubMedID- 20609696 | These agents may expand the utility of beta-blockers to patient populations traditionally considered not to be optimal candidates for beta-blocker therapy-a fact which has important clinical implications, because more antihypertensive agents are needed to diversify the therapeutic options available for clinicians treating hypertension in patients with the cardiometabolic syndrome or type 2 diabetes. |
| PubMedID- 25615826 | Medical costs for people with obesity are approximately 30% greater than for people with normal weights, because obesity is related to serious health problems such as diabetes, hypertension, and other components of metabolic syndrome [3]. |
| PubMedID- 24467657 | These results suggest that increases in atp content in rvlm is engaged in the augmented sympathetic vasomotor activity and hypertension associated with metabolic syndrome induced by the hfd. |
| PubMedID- 22474523 | Type 2 dm can induce insulin resistance syndrome, which is associated with obesity, hyperlipidemia, hypertension, atherosclerotic heart disease, and other systemic diseases [3, 4]. |
| PubMedID- 23318820 | Introduction: the treatment of arterial hypertension (ah) in patients with metabolic syndrome (ms) is a challenge, since non drug therapies are difficult to implement and optimal pharmacological treatment is not fully established. |
| PubMedID- 25758604 | Impaired right ventricular hemodynamics indicate preclinical pulmonary hypertension in patients with metabolic syndrome. |
| PubMedID- 22190906 | Vascular endothelial dysfunction has been demonstrated in metabolic syndrome with and without hypertension or diabetes [1–3]. |
| PubMedID- 23931752 | The role of the sympathetic nervous system, stress, and hypertension in metabolic syndrome and obesity remains unclear. |
| PubMedID- 22293193 | Salt-sensitive hypertension is a characteristic of the metabolic syndrome. |
| PubMedID- 25906108 | hypertension, a component of the metabolic syndrome, was indicated to be associated with prostate cancer.17,43,44 however, not all epidemiological studies have supported this link.12,13 in this study, more prostate patients were observed in the hypertension group, but the difference did not reach the statistically significant level (adjusted hr = 1.20, 95% ci = 0.97–1.47). |
| PubMedID- 21773016 | In addition, there is mounting evidence that chronic psychological stress and negative mood states are strongly associated, in a bidirectional manner, with insulin resistance, glucose intolerance, central obesity, dyslipidemia, hypertension, and other components of the metabolic syndrome [19–25]. |
| PubMedID- 23112423 | Objective: obesity plays a central role in the insulin resistance syndrome, which is associated with hyperinsulinemia, hypertension, hyperlipidemia, type 2 diabetes mellitus, and an increased risk of atherosclerotic cardiovascular disease. |
| PubMedID- 20921214 | Whether this association holds true in primary hypertension and is independent of renal function and metabolic syndrome is not clear at present. |
| PubMedID- 22305998 | A subgroup analysis in patients with hypertension and comorbidities of diabetes, cardiometabolic syndrome, or obesity, and in black participants is reported. |
| PubMedID- 21155616 | Background and objective: metabolic syndrome is common in patients with hypertension and increases the risk of developing diabetes mellitus. |
| PubMedID- 23629805 | Thus, shrcp are regarded as a useful model of human hypertension with metabolic syndrome. |
| PubMedID- 22940679 | Objective: nonalcoholic fatty liver and hypertension are associated with metabolic syndrome. |
| PubMedID- 21471972 | There is evidence that uncontrolled arterial hypertension (aht) in patients with metabolic syndrome (ms) increases cardiovascular risks. |
| PubMedID- 20383279 | Whereas arbs and acei have demonstrated their efficiency in improving insulin sensitivity and reducing end-organ damage and are now often considered as first-line therapy in hypertension with metabolic syndrome or diabetes [3], [4], [5], [30], association of anti-oxidants or anti-nitrants in an attempt to further reduce deleterious nitrative stress might be worth considering in severely affected or non-responsive patients. |
| PubMedID- 22846983 | Targeting hypertension in patients with cardiorenal metabolic syndrome. |
| PubMedID- 22470194 | Nafld is usually part of the metabolic syndrome, found namely in patients with diabetes mellitus, hypertension, dyslipidemia, obesity and insulin resistance, which is becoming very frequent in western populations, due to their life style (sedentariness) and diet. |
| PubMedID- 22422828 | hypertension as part of the metabolic syndrome has been frequently related to end-stage renal disease. |
| PubMedID- 22534714 | Obesity and arterial hypertension are both components of metabolic syndrome; moreover, adipose tissue is considered to be a potent hypertensive agent. |
| PubMedID- 23524523 | Objective: obesity, diabetes, fatty liver, and hypertension are major determinants of the metabolic syndrome. |
| PubMedID- 24417059 | Clinical features of arterial hypertension in patients with metabolic syndrome are described with reference to antihypertensive therapy and the choice of adequate drugs for the purpose. |
| PubMedID- 21143427 | Dietary fructose, salt absorption and hypertension in metabolic syndrome: towards a new paradigm. |
| PubMedID- 20718958 | The possible mechanisms that trigger arterial hypertension associated with metabolic syndrome are mainly related to the presence of visceral fat, which results in insulin resistance. |
| PubMedID- 23024568 | The comorbid relationship between stroke and migraine may relate to observations that migraineurs have increased adiposity, reduced insulin sensitivity, an unfavourable lipid profile and hypertension, all features of the metabolic syndrome, a known risk factor for cerebrovascular disease. |
| PubMedID- 21107432 | The prevalence of metabolic syndrome (mets) in patients with essential hypertension is very high, and has been estimated as being close to 50%.1 hypertensive patients with mets have a much higher cardiovascular (cv) risk than their counterparts without mets,2 and also have a particularly high risk of developing type 2 diabetes mellitus (t2dm).3 in addition, the choice of antihypertensive therapy can have a large impact on the risk of development of t2dm.4 renin–angiotensin system blockers, that is, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers (arbs), improve insulin sensitivity and reduce the risk of developing t2dm compared with placebo, whereas calcium channel blockers (ccbs) have a neutral effect. |
| PubMedID- 22963383 | We describe a rat model for maladaptive cardiac remodeling in obesity and metabolic syndrome associated with hypertension, a common comorbid condition, gaining increasing relevance. |
| PubMedID- 21516767 | [pathogenetic aspects of arterial hypertension in metabolic syndrome]. |
| PubMedID- 24441717 | Although a wide range of potentially therapeutic effect of asiatic acid have been reported, little is known about the effect of asiatic acid on metabolic syndrome associated with hypertension in diet-induced ms. the aim of the present study was to investigate whether asiatic acid can improve metabolic and cardiovascular complications in an animal model of hchf diet-induced metabolic syndrome. |
| PubMedID- 22728908 | Objectives: renin-angiotensin system inhibitors are preferred for the treatment of hypertension with metabolic syndrome (mets). |
| PubMedID- 20795419 | metabolic syndrome in patients with hypertension attending a family practice clinic in jordan. |
| PubMedID- 22030814 | This monosaccharide is linked to metabolic syndrome, being associated with hypertriglyceridemia, hypertension, insulin resistance and diabetes mellitus. |
| PubMedID- 25875942 | Non-alcoholic fatty liver disease (nafld) is the most common cause of hepatic disease in western civilization [1] and is considered as a hepatic manifestation of a metabolic syndrome strongly associated with dyslipidemia, obesity, hypertension and insulin resistance[2]. |