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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease metabolic syndrome x
Comorbidity C0004153|atherosclerosis
Sentences 37
PubMedID- 21827549 Background: carotid intima-media thickness (cimt) is a potential indicator of subclinical atherosclerosis in patients with metabolic syndrome (mets).
PubMedID- 22493605 Background: the renin-angiotensin-aldosterone system plays an important role in the development and progression of hypertension and accelerated atherosclerosis (atheroscleropathy) associated with the cardiorenal metabolic syndrome and type 2 diabetes mellitus.
PubMedID- 24470352 Also observed defects in akt2 signaling which may contribute to accelerated atherosclerosis in patients with metabolic syndrome (18).
PubMedID- 23798936 A recent population-based study reported that the association of a metabolic syndrome with subclinical atherosclerosis was independent of its association with the biomarkers of endothelial damage and oxidative stress.
PubMedID- 20705925 Methods and results: atm(+/-)/apoe(-/-) mice developed accelerated atherosclerosis and multiple features of the metabolic syndrome, including hypertension, hypercholesterolemia, obesity, steatohepatitis, and glucose intolerance.
PubMedID- 23776788 [2] il-6 has also been reported to play a role in the development of atherosclerosis complications in patients with metabolic syndrome.
PubMedID- 21497934 Aim: the goal of this study was to investigate the association between omentin-1 and carotid atherosclerosis in patients with metabolic syndrome (mets).
PubMedID- 25633268 Aims: matrix metalloproteinases (mmps) and their tissue inhibitors (timps) are dysregulated in metabolic syndrome (mets) and associated with atherosclerosis and cardiovascular disease (cvd).
PubMedID- 24072083 Carotid intima-media thickness (imt) is a potential indicator of subclinical atherosclerosis in patients with metabolic syndrome (ms).
PubMedID- 24481091 [relation between mean platelet volume and subclinical atherosclerosis in patients with metabolic syndrome].
PubMedID- 21321616 [detection of the parameters for early atherosclerosis in patients with metabolic syndrome and periodontitis].
PubMedID- 20039893 The metabolic syndrome is associated with subclinical atherosclerosis independent of insulin resistance: the guangzhou biobank cohort study-cvd.
PubMedID- 20470376 Association between serum levels of incretins, glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip), and metabolic syndrome components in patients with atherosclerosis-prone conditions.
PubMedID- 21505504 Our results suggest that these processes are associated with atherosclerosis independent of metabolic syndrome.
PubMedID- 20727144 Subclinical carotid atherosclerosis is associated with metabolic syndrome [38].
PubMedID- 19762024 The incremental role of obstructive sleep apnoea on markers of atherosclerosis in patients with metabolic syndrome.
PubMedID- 23398954 Associations of cxcl16/cxcr6 with carotid atherosclerosis in patients with metabolic syndrome.
PubMedID- 23245314 Decreased serum obestatin consequent upon trib3 q84r polymorphism exacerbates carotid atherosclerosis in subjects with metabolic syndrome.
PubMedID- 25546822 Interestingly, therefore, myd88-dependent cooperation between myeloid and endothelial cells was recently proven to be key to the promotion of the vascular inflammation and atherosclerosis associated with metabolic syndrome 64. thus, because myd88 is likely to be a key player in integrating cross-talk among tlr, fcr, and complement receptors, in concert with the reduction in igg and c3a deposition, our finding that es-62 and anti–il-22 down-regulate myd88 expression in kidney cells provides an effective mechanism for protecting against kidney inflammation.
PubMedID- 20689417 Recent findings: individuals infected with hiv frequently demonstrate a metabolic syndrome associated with atherosclerosis and cardiovascular disease.
PubMedID- 22748277 Nonalcoholic fatty liver disease is associated with subclinical atherosclerosis independent of obesity and metabolic syndrome in asian indians.
PubMedID- 24490696 Tempol attenuates atherosclerosis associated with metabolic syndrome via decreased vascular inflammation and nadph-2 oxidase expression.
PubMedID- 25233795 Association of metabolic syndrome with coronary atherosclerosis in non-diabetic postmenopausal women.
PubMedID- 21772967 Based on this data and the sparcl (stroke prevention by aggressive reduction in cholesterol levels) trial [75], the recommendation is for aggressive lipid lowering with statin in patients with atherosclerotic ischemic stroke.another wasid substudy [76] has demonstrated that metabolic syndrome is associated with intracranial atherosclerosis and confers a higher risk of major vascular events in these patients.
PubMedID- 22813569 Association of metabolic syndrome with carotid atherosclerosis in the young north indian population.
PubMedID- 22291799 In our study, the level of inflammatory markers crp and tnf-α, agents of the coagulation system activation and fibrinolysis (d-dimers, fibrinogen) participating in the inflammatory process of atherosclerosis were higher in patients with the metabolic syndrome as compared with healthy women.
PubMedID- 21251304 Circulating interleukin-18: a specific biomarker for atherosclerosis-prone patients with metabolic syndrome.
PubMedID- 25242580 Therefore, the intervention with anti-inflammatory agents may effectively delay the formation and progression of atherosclerosis in patients with metabolic syndrome.
PubMedID- 23409033 Implication of progranulin and c1q/tnf-related protein-3 (ctrp3) on inflammation and atherosclerosis in subjects with or without metabolic syndrome.
PubMedID- 19968738 This combination of metabolic syndrome factors was associated with accelerated atherosclerosis due to increased accumulation of macrophages in association with endothelial dysfunction demonstrated by increased expression of vcam-1 and icam-1 in the aorta of dko mice [49].
PubMedID- 20398632 Background: oxidative stress induced by free fatty acids plays a critical role in the pathogenesis of endothelial dysfunction and atherosclerosis in patients with metabolic syndrome.
PubMedID- 22765047 Ir and other features of the metabolic syndrome independently associate with atherosclerosis in ra [46].
PubMedID- 21816063 Furthermore, our findings suggest that the observed association between uric acid and carotid atherosclerosis may be attributed to metabolic syndrome-dependent and -independent mechanisms.
PubMedID- 20187939 Low hdl is often accompanied by insulin resistance, obesity, and hypertension, which are risk factors for atherosclerosis and are components of the metabolic syndrome [23,43].
PubMedID- 21669554 Apolipoprotein e−/− (apoe−/−) mice heterozygous in atm developed accelerated atherosclerosis and multiple features of the metabolic syndrome including glucose intolerance, hypertension, obesity and hypercholesterolemia [22,23].
PubMedID- 25218813 Circulating osteoprotegerin is increased in the metabolic syndrome and associates with subclinical atherosclerosis and coronary arterial calcification.
PubMedID- 25951321 Klotho did not show any beneficial effects on atherosclerosis and components of the metabolic syndrome and was associated with increased plasma cholesterol levels.

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