eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | metabolic syndrome x |
| Comorbidity | C0002395|alzheimer\'s disease |
| Sentences | 5 |
| PubMedID- 20383813 | Hyperhomocysteinemia and homozygous mthfr 677c>t mutation finding in an alzheimer's disease case with metabolic syndrome diagnosis. |
| PubMedID- 25191597 | alzheimer's disease has beenassociated with the metabolic syndrome in humans(14) and wistar kyoto rats fed a hfd show increases in the levels ofbiomarkers for alzheimer's disease(15). |
| PubMedID- 21726644 | Although the enhanced risk of alzheimer's disease in metabolic syndrome is related to several factors, our results suggest that srebp2, which can be modulated by the impairment of cerebral cholesterol homeostasis, has a direct role on bace1 expression and may be involved in alzheimer's disease progression. |
| PubMedID- 21457772 | The role of iron in catalyzing fenton-mediated oxidative damage has been implicated in iron overload genetic diseases, carcinogenesis (colon cancer), alzheimer's disease and complications associated with the metabolic syndrome through the generation of reactive oxygen species (ros). |
| PubMedID- 23142434 | Background: accumulating evidence indicates an association of alzheimer's disease (ad) with the metabolic syndrome (mets), characterized by visceral fat accumulation with insulin resistance and altered secretion of adipocytokines such as adiponectin and leptin. |
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